Reply to “Pure autonomic failure vs. Manifest CNS synucleinopathy: Relevance of stridor and autonomic biomarkers”
Sign Up to like & getrecommendations! Published in 2017 at "Annals of Neurology"
DOI: 10.1002/ana.24949
Abstract: We read with interest the excellent seminal study of Kaufmann et al demonstrating the natural history of pure autonomic failure (PAF). We offer the following comments. The authors found several distinguishing features predicting whether the… read more here.
Keywords: autonomic failure; stridor; lewy body; body disease ... See more keywords
Effects of Alzheimer and Lewy Body Disease Pathologies on Brain Metabolism
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Neurology"
DOI: 10.1002/ana.26355
Abstract: This study aimed to determine the pattern of 18F‐fluorodeoxyglucose positron emission tomography (FDG‐PET) related to postmortem Lewy body disease (LBD) pathology in clinical Alzheimer disease (AD). read more here.
Keywords: disease; effects alzheimer; body disease; alzheimer lewy ... See more keywords
Illusory Responses across the Lewy Body Disease Spectrum
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DOI: 10.1002/ana.26574
Abstract: This study was undertaken to study pareidolias, or perceived meaningful objects in a meaningless stimulus, in patients across the Lewy body (LB) disease spectrum, where most do not report hallucinations or delusions. read more here.
Keywords: body disease; across lewy; lewy body; disease spectrum ... See more keywords
Structural connectivity networks in Alzheimer’s disease and Lewy body disease
Sign Up to like & getrecommendations! Published in 2021 at "Brain and Behavior"
DOI: 10.1002/brb3.2112
Abstract: We evaluated disruption of the white matter (WM) network related with Alzheimer's disease (AD) and Lewy body disease (LBD), which includes Parkinson's disease and dementia with Lewy bodies. read more here.
Keywords: disease lewy; alzheimer disease; disease; body disease ... See more keywords
Effect of biological treatments on psychotic symptoms in lewy body disease: A systematic review and meta‐analysis of randomized controlled trials
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Geriatric Psychiatry"
DOI: 10.1002/gps.5376
Abstract: Parkinson disease and dementia with Lewy bodies (collectively termed Lewy body disease) are common neurodegenerative conditions of later life and are frequently associated with distressing psychotic symptoms. The best approach to manage these symptoms is… read more here.
Keywords: disease; body disease; psychotic symptoms; effect biological ... See more keywords
GBE1‐related disorders: Adult polyglucosan body disease and its neuromuscular phenotypes
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Inherited Metabolic Disease"
DOI: 10.1002/jimd.12325
Abstract: Adult polyglucosan body disease (APBD) represents a complex autosomal recessive inherited neurometabolic disorder due to homozygous or compound heterozygous pathogenic variants in GBE1 gene, resulting in deficiency of glycogen‐branching enzyme and secondary storage of glycogen… read more here.
Keywords: adult polyglucosan; polyglucosan body; disease; body disease ... See more keywords
Methylation changes and aberrant expression of FGFR3 in Lewy body disease neurons
Sign Up to like & getrecommendations! Published in 2018 at "Brain Research"
DOI: 10.1016/j.brainres.2018.06.017
Abstract: Lewy body disease (LBD) is characterized by accumulation of aggregated α-synuclein in the central nervous system as eosinophilic cytoplasmic inclusions called Lewy bodies. According to their distribution pattern, it is classified into brainstem LBD, limbic… read more here.
Keywords: methylation; lbd; body disease; lewy ... See more keywords
Neuroimaging findings and clinical trajectories of Lewy body disease in patients with MCI
Sign Up to like & getrecommendations! Published in 2019 at "Neurobiology of Aging"
DOI: 10.1016/j.neurobiolaging.2018.12.001
Abstract: Elderly patients with mild cognitive impairment (MCI) may develop a Lewy body disease; their neuroimaging features at presentation are largely unknown. We present an intriguing group of 13 patients with MCI preceding (2.9 ± 1.9 years)… read more here.
Keywords: patients mci; disease; body disease; neuroimaging findings ... See more keywords
Neurodegenerative disease concomitant proteinopathies are prevalent, age-related and APOE4-associated
Sign Up to like & getrecommendations! Published in 2018 at "Brain"
DOI: 10.1093/brain/awy146
Abstract: Lewy bodies commonly occur in Alzheimer's disease, and Alzheimer's disease pathology is frequent in Lewy body diseases, but the burden of co-pathologies across neurodegenerative diseases is unknown. We assessed the extent of tau, amyloid-β, α-synuclein… read more here.
Keywords: alzheimer disease; disease; body disease; pathology ... See more keywords
Case report: Late‐onset mania as a presentation of underlying Lewy body disease
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DOI: 10.1111/bdi.13200
Abstract: We describe an older adult presenting with a first manic episode whose neuroimaging findings were consistent with Lewy body disease. Given recent growing evidence on its clinical diversity, it is important to consider that Lewy… read more here.
Keywords: report late; case report; body disease; lewy body ... See more keywords
Neuropathological studies of serotonergic and noradrenergic systems in Lewy body disease patients with delusion or depression
Sign Up to like & getrecommendations! Published in 2022 at "Psychiatry and Clinical Neurosciences"
DOI: 10.1111/pcn.13436
Abstract: The association between psychiatric symptoms in Lewy body disease (LBD) and the noradrenergic and serotonergic systems is still controversial. This study investigated the quantitative relationships of depression and delusion with these systems. read more here.
Keywords: neuropathological studies; depression; body disease; lewy body ... See more keywords