Parafoveal thinning of inner retina is associated with visual dysfunction in Lewy body diseases
Sign Up to like & getrecommendations! Published in 2019 at "Movement Disorders"
DOI: 10.1002/mds.27728
Abstract: Retinal optical coherence tomography findings in Lewy body diseases and their implications for visual outcomes remain controversial. We investigated whether region‐specific thickness analysis of retinal layers could improve the detection of macular atrophy and unravel… read more here.
Keywords: inner retina; parafoveal thinning; body diseases; thinning inner ... See more keywords
Cross-platform transcriptional profiling identifies common and distinct molecular pathologies in Lewy body diseases
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DOI: 10.1007/s00401-021-02343-x
Abstract: Parkinson’s disease (PD), Parkinson’s disease with dementia (PDD) and dementia with Lewy bodies (DLB) are three clinically, genetically and neuropathologically overlapping neurodegenerative diseases collectively known as the Lewy body diseases (LBDs). A variety of molecular… read more here.
Keywords: platform transcriptional; body diseases; cross platform; pdd dlb ... See more keywords
Therapeutic approaches to cholinergic deficiency in Lewy body diseases
Sign Up to like & getrecommendations! Published in 2019 at "Expert Review of Neurotherapeutics"
DOI: 10.1080/14737175.2020.1676152
Abstract: ABSTRACT Introduction: Cortical cholinergic denervation resulting from degeneration of the nucleus basalis of Meynert (NBM) is a primary contributor to cognitive impairment and neuropsychiatric symptoms in the Lewy body diseases Parkinson’s disease (PD), Parkinson’s disease… read more here.
Keywords: cholinergic deficiency; body diseases; lewy body; cortical cholinergic ... See more keywords