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1
Published in 2022 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51657
Abstract: Sporadic inclusion body myositis (sIBM) is the most common acquired myopathy in patients older than 50 years of age. sIBM is hardly responds to any immunosuppressing theraphies, and its pathophysiology remains elusive. This study aims to…
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Keywords:
inclusion body;
sporadic inclusion;
body myositis;
metabolome transcriptome ... See more keywords
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0
Published in 2017 at "Annals of Neurology"
DOI: 10.1002/ana.24919
Abstract: Sporadic inclusion body myositis (sIBM), an intractable progressive muscle disease, frequently occurs in older persons. sIBM pathogenesis may involve protein degradation dysfunction and immune abnormalities. Autoantibodies recognizing cytosolic 5′‐nucleotidase 1A (cN1A) were found in plasma…
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Keywords:
body myositis;
cytosolic nucleotidase;
sporadic inclusion;
inclusion body ... See more keywords
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2
Published in 2023 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.13178
Abstract: Inclusion body myositis (IBM) is an inflammatory myopathy clinically characterized by proximal and distal muscle weakness, with inflammatory infiltrates, rimmed vacuoles and mitochondrial changes in muscle histopathology. There is scarce knowledge on IBM aetiology, and…
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Keywords:
inclusion body;
body myositis;
unravelling inclusion;
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0
Published in 2018 at "Rheumatology International"
DOI: 10.1007/s00296-018-4221-z
Abstract: Sporadic inclusion body myositis (s-IBM) is a progressive, skeletal muscle disease with poor prognosis. However, establishing the final diagnosis is difficult because of the lack of clear biomarkers in the blood serum and very slow…
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Keywords:
sporadic inclusion;
microscopy;
immunohistochemical ultrastructural;
rheumatology ... See more keywords
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0
Published in 2019 at "eNeurologicalSci"
DOI: 10.1016/j.ensci.2019.100204
Abstract: Inclusion body myositis (IBM) is the commonest idiopathic inflammatory myopathy of older persons. Pathophysiological mechanism of IBM remains unknown; however, an association of IBM with chronic hepatitis C virus (HCV) infection and serum autoantibodies against…
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Keywords:
hepatitis;
treatment;
therapy;
inclusion body ... See more keywords
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0
Published in 2017 at "Journal of the Neurological Sciences"
DOI: 10.1016/j.jns.2017.08.2306
Abstract: disease characterized by remittent fever, skin rash, emaciation of the face and upper body, and long gnarled fingers with contractures. Mutation of the gene encoding the β5i subunit of the immunoproteasome causes the accumulation of…
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Keywords:
pathological features;
clinical pathological;
body myositis;
inclusion body ... See more keywords
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Published in 2019 at "Neuromuscular Disorders"
DOI: 10.1016/j.nmd.2019.02.001
Abstract: Sporadic inclusion body myositis (sIBM) is a late onset disorder of unkown aetiology. Mitochondrial changes such as cytochrome oxidase deficient fibres are a well recognised feature and mitochondrial DNA (mtDNA) deletions have also been reported,…
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Keywords:
sporadic inclusion;
mtdna;
body myositis;
mitochondrial dna ... See more keywords
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2
Published in 2020 at "Neuromuscular Disorders"
DOI: 10.1016/j.nmd.2020.02.010
Abstract: Inclusion Body Myositis (IBM) is the most common acquired myopathy in older individuals with more than two thirds of patients experiencing impaired swallowing. There are currently no standardized exercise therapies to improve or sustain swallowing…
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Keywords:
muscle strength;
expiratory muscle;
pilot study;
pilot ... See more keywords
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0
Published in 2020 at "Neuromuscular Disorders"
DOI: 10.1016/j.nmd.2020.08.358
Abstract: Inclusion body myositis is the most commonly acquired myopathy after the age of 45. The slowly progressive and heterogeneous disorder is a challenge for measuring clinical trial efficacy. One current method for measuring progression utilizes…
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Keywords:
body myositis;
inclusion body;
outcome measures;
patient ... See more keywords
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Published in 2021 at "Journal of neuropathology and experimental neurology"
DOI: 10.1093/jnen/nlab101
Abstract: To review our diagnostic and treatment approaches concerning sporadic inclusion body myositis (sIBM) and polymyositis with mitochondrial pathology (PM-Mito), we conducted a retrospective analysis of clinical and histological data of 32 patients diagnosed as sIBM…
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Keywords:
mitochondrial pathology;
sporadic inclusion;
pathology;
body myositis ... See more keywords
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Published in 2020 at "International Journal of Rheumatic Diseases"
DOI: 10.1111/1756-185x.13902
Abstract: Inclusion body myositis is a rare sporadic inflammatory‐degenerative myopathy of the elderly. Despite being the commonest type of acquired myopathy after the age of 50, misdiagnosis is extremely common. The most frequent hurdle in identifying…
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Keywords:
rheumatology;
inclusion body;
body myositis;