Intrinsically Disordered Protein Condensate-Modified Surface for Mitigation of Biofouling and Foreign Body Response.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c02677
Abstract: Mitigation of biofouling and the host's foreign body response (FBR) is a critical challenge with biomedical implants. The surface coating with various anti-fouling materials provides a solution to overcome it, but limited options in clinic… read more here.
Keywords: body response; foreign body; intrinsically disordered; mitigation biofouling ... See more keywords
The surface topography of silicone breast implants mediates the foreign body response in mice, rabbits and humans.
Sign Up to like & getrecommendations! Published in 2021 at "Nature biomedical engineering"
DOI: 10.1038/s41551-021-00739-4
Abstract: Silicone is widely used in chronic implants and is generally perceived to be safe. However, textured breast implants have been associated with immune-related complications, including malignancies. Here, by examining for up to one year the… read more here.
Keywords: topography; breast implants; foreign body; body response ... See more keywords
Exploring the Overlooked Roles and Mechanisms of Fibroblasts in the Foreign Body Response.
Sign Up to like & getrecommendations! Published in 2022 at "Advances in wound care"
DOI: 10.1089/wound.2022.0066
Abstract: Significance Foreign body response (FBR), wherein a fibrotic capsule forms around an implanted structure, is a common surgical complication that often leads to pain, discomfort, and eventual revision surgeries. Though believed to have some mechanistic… read more here.
Keywords: body response; foreign body; exploring overlooked; overlooked roles ... See more keywords
Mesenchymal stem cell-based bioengineered constructs: foreign body response, cross-talk with macrophages and impact of biomaterial design strategies for pelvic floor disorders
Sign Up to like & getrecommendations! Published in 2019 at "Interface Focus"
DOI: 10.1098/rsfs.2018.0089
Abstract: An excessive foreign body response (FBR) has contributed to the adverse events associated with polypropylene mesh usage for augmenting pelvic organ prolapse surgery. Consequently, current biomaterial research considers the critical role of the FBR and… read more here.
Keywords: pelvic floor; response; foreign body; body response ... See more keywords
Cochlear implant material effects on inflammatory cell function and foreign body response
Sign Up to like & getrecommendations! Published in 2022 at "Hearing Research"
DOI: 10.1101/2022.06.20.496419
Abstract: Objectives The objectives of this study were to assess the effects of cochlear implant (CI) biomaterials on the function of macrophages and fibroblasts, two key mediators of the foreign body response (FBR) and to determine… read more here.
Keywords: cell; cochlear implant; body response; microscopy ... See more keywords
Reduction of the foreign body response and neuroprotection by apyrase and minocycline in chronic cannula implantation in the rat brain
Sign Up to like & getrecommendations! Published in 2017 at "Clinical and Experimental Pharmacology and Physiology"
DOI: 10.1111/1440-1681.12703
Abstract: Implantation of electrodes or cannulae into the brain is accompanied by a tissue response referred to as foreign body response. Adenosine triphosphate (ATP) is one of the signalling molecules released by injured cells which mediate… read more here.
Keywords: response; foreign body; body response; implantation ... See more keywords
Deep Learning for Automated Analysis of Cellular and Extracellular Components of the Foreign Body Response in Multiphoton Microscopy Images
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2021.797555
Abstract: The Foreign body response (FBR) is a major unresolved challenge that compromises medical implant integration and function by inflammation and fibrotic encapsulation. Mice implanted with polymeric scaffolds coupled to intravital non-linear multiphoton microscopy acquisition enable… read more here.
Keywords: body response; microscopy; foreign body; cellular extracellular ... See more keywords
Transcriptomic Analysis in Human 3D Skin Model Injected with Resorbable Hyaluronic Acid Fillers Reveals Foreign Body Response
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232113046
Abstract: Usage of injectable dermal fillers applied for aesthetic purposes has extensively increased over the years. As such, the number of related adverse reactions has increased, including patients showing severe complications such as product migration, topical… read more here.
Keywords: skin model; skin; body response; foreign body ... See more keywords
A Polymer-Biologic Hybrid Hernia Construct: Review of Data and Early Experiences
Sign Up to like & getrecommendations! Published in 2021 at "Polymers"
DOI: 10.3390/polym13121928
Abstract: Surgical mesh reinforcement of the human abdominal wall has been found to reduce the chance of recurrence in hernia repairs. While traditionally polymer meshes have been used in hernia repair, alternative mesh options have been… read more here.
Keywords: hernia; hernia repair; response; foreign body ... See more keywords
Towards a Whole Sample Imaging Approach Using Diffusion Tensor Imaging to Examine the Foreign Body Response to Explanted Medical Devices
Sign Up to like & getrecommendations! Published in 2022 at "Polymers"
DOI: 10.3390/polym14224819
Abstract: Analysing the composition and organisation of the fibrous capsule formed as a result of the Foreign Body Response (FBR) to medical devices, is imperative for medical device improvement and biocompatibility. Typically, analysis is performed using… read more here.
Keywords: fibrous capsule; medical devices; body response; sample imaging ... See more keywords