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Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2023.1987
Abstract: Key Points Question How are body weight and change in body weight over time associated with the risk of hypertension in youths at the higher end of normal weight? Findings In this cohort study including…
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Keywords:
risk hypertension;
hypertension;
change;
body weight ... See more keywords
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1
Published in 2018 at "Birth Defects Research"
DOI: 10.1002/bdr2.1214
Abstract: Physiologically based pharmacokinetic (PBPK) models are developed from compound‐independent information to describe important anatomical and physiological characteristics of an individual or population of interest. Modeling pediatric populations is challenging because of the rapid changes that…
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Keywords:
growth equations;
full term;
age;
growth ... See more keywords
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Published in 2020 at "Clinical Pharmacology in Drug Development"
DOI: 10.1002/cpdd.871
Abstract: Treatment of Chagas disease with nifurtimox requires age‐ and body weight‐adjusted dosing, resulting in complex dosing instructions. Appropriate formulations are needed for precise and compliant dosing, especially in pediatric patients. We characterized the biopharmaceutical features…
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Keywords:
auc0 tlast;
age body;
adjusted dosing;
weight adjusted ... See more keywords
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Published in 2021 at "Clinical pharmacology and therapeutics"
DOI: 10.1002/cpt.2467
Abstract: Our research supported the dose selection recommendations for adolescents in the FDA Guidance on Inclusion of Adolescent Patients in Adult Oncology Clinical Trials. The FDA Guidance states that for drugs administered as a flat dose…
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Keywords:
adult oncology;
oncology clinical;
clinical trials;
body weight ... See more keywords
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1
Published in 2021 at "Environmental toxicology and chemistry"
DOI: 10.1002/etc.5045
Abstract: Plant protection products, including insecticides, are important for global food production, but can have adverse effects on non-target organisms including bees. Historically, research investigating such effects has focused mainly on the honeybee (Apis mellifera), while…
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Keywords:
sensitivity;
acute contact;
body weight;
bee sensitivity ... See more keywords
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1
Published in 2019 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.9610
Abstract: BACKGROUND Egg yolks contain large amounts of cholesterol and are suspected to be harmful after long-term consumption. In this experiment, 63 rats were used to evaluate the effect of egg white (EW) and egg yolk…
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Keywords:
egg;
expression;
rats fed;
brain ... See more keywords
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Published in 2017 at "Obesity"
DOI: 10.1002/oby.21713
Abstract: Dimensions of impulsivity are related to obesity. Accordingly, characterization of impulsivity in individuals with overweight and obesity holds promise for more targeted and effective intervention.
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Keywords:
impulsivity body;
weight integrating;
study impulsivity;
body weight ... See more keywords
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Published in 2019 at "Obesity"
DOI: 10.1002/oby.22391
Abstract: This study aimed to examine the association between birth weight (BW) and metabolic syndrome (MetS) in adolescents and to further investigate whether having a healthy body weight could modify the potential adverse influence of abnormal…
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Keywords:
weight metabolic;
healthy body;
birth weight;
metabolic syndrome ... See more keywords
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1
Published in 2021 at "Obesity"
DOI: 10.1002/oby.23080
Abstract: Physiological adaptations to intentional weight loss can facilitate weight regain. This review summarizes emerging findings on hypothalamic and brainstem circuitry in the regulation of body weight and identifies promising areas for research to improve therapeutic…
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Keywords:
obesity;
physiology;
body weight;
energy ... See more keywords
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Published in 2021 at "Obesity"
DOI: 10.1002/oby.23091
Abstract: This study investigated the association between ultraprocessed food consumption and excess body weight in a Swiss nationally representative study.
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Keywords:
excess body;
food consumption;
ultraprocessed food;
weight swiss ... See more keywords
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2
Published in 2022 at "Obesity"
DOI: 10.1002/oby.23355
Abstract: The aim of this study was to report the level and trends of 13 cancers that are attributable to excess body weight (EBW) for 204 countries and territories from 1990 to 2019.
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Keywords:
excess body;
204 countries;
countries territories;
body weight ... See more keywords