Overweight Kidney Transplant Recipients Are at Risk of Being Overdosed Following Standard Bodyweight-Based Tacrolimus Starting Dose
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DOI: 10.1097/txd.0000000000000644
Abstract: Background Bodyweight-based dosing of tacrolimus (Tac) is considered standard care, even though the available evidence is thin. An increasing proportion of transplant recipients is overweight, prompting the question if the starting dose should always be… read more here.
Keywords: starting dose; following standard; standard bodyweight; bodyweight based ... See more keywords
Impact of bodyweight‐based starting doses on the safety and efficacy of lenvatinib in primarily Japanese patients with hepatocellular carcinoma
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DOI: 10.1111/hepr.13800
Abstract: The phase III REFLECT study utilized bodyweight‐based lenvatinib dosing in patients with unresectable hepatocellular carcinoma, based on results of the phase II Study 202. This post hoc analysis compared efficacy and safety in patients with… read more here.
Keywords: bodyweight based; hepatocellular carcinoma; safety; efficacy ... See more keywords