β-cantenin is potentially involved in the regulation of c-Jun signaling following bovine herpesvirus 1 infection
Sign Up to like & getrecommendations! Published in 2020 at "Veterinary Microbiology"
DOI: 10.1016/j.vetmic.2020.108804
Abstract: Abstract C-Jun, activated by various extracellular signals, is important for cell differentiation, proliferation, apoptosis, and inflammatory responses. We have previously reported that bovine herpesvirus 1 (BoHV-1) infection in MDBK cells stimulates the c-Jun NH2-terminal kinase… read more here.
Keywords: jun; bovine herpesvirus; infection; bohv infection ... See more keywords
Bovine Herpesvirus 1 Productive Infection Led to Inactivation of Nrf2 Signaling through Diverse Approaches
Sign Up to like & getrecommendations! Published in 2019 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2019/4957878
Abstract: Bovine herpesvirus type 1 (BoHV-1) is a significant cofactor for bovine respiratory disease complex (BRDC), the most important inflammatory disease in cattle. BoHV-1 infection in cell cultures induces overproduction of pathogenic reactive oxygen species (ROS)… read more here.
Keywords: bovine herpesvirus; infection; nrf2 signaling; bohv infection ... See more keywords
The role of phospholipase C signaling in bovine herpesvirus 1 infection
Sign Up to like & getrecommendations! Published in 2017 at "Veterinary Research"
DOI: 10.1186/s13567-017-0450-5
Abstract: Bovine herpesvirus 1 (BoHV-1) infection enhanced the generation of inflammatory mediator reactive oxidative species (ROS) and stimulated MAPK signaling that are highly possibly related to virus induced inflammation. In this study, for the first time… read more here.
Keywords: bovine herpesvirus; infection; bohv infection; activation ... See more keywords
Comparative transcriptome analysis of MDBK cells reveals that BoIFN-γ augmented host immune responses to bovine herpesvirus 1 infection
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.973278
Abstract: Bovine herpesvirus 1 (BoHV-1) is an alphaherpesvirus that causes infectious bovine rhinotracheitis and infectious pustular vulvovaginitis in cattle. Ιnterferon-gamma (IFN-γ) is a pleiotropic cytokine with antiviral activity that modulates the innate and adaptive immune responses.… read more here.
Keywords: host; bohv infection; infection; mdbk cells ... See more keywords
β-Catenin-Specific Inhibitor, iCRT14, Promotes BoHV-1 Infection-Induced DNA Damage in Human A549 Lung Adenocarcinoma Cells by Enhancing Viral Protein Expression
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23042328
Abstract: Oncolytic bovine herpesvirus type 1 (BoHV-1) infection induces DNA damage in human lung adenocarcinoma cell line A549. However, the underlying mechanisms are not fully understood. We found that BoHV-1 infection decreased the steady-state protein levels… read more here.
Keywords: damage; bohv infection; dna damage; catenin ... See more keywords
Induction of the Unfolded Protein Response during Bovine Alphaherpesvirus 1 Infection
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DOI: 10.3390/v12090974
Abstract: Bovine herpesvirus 1 (BoHV-1) is an alphaherpesvirus that causes great economic losses in the cattle industry. Herpesvirus infection generally induces endoplasmic reticulum (ER) stress, and the unfolded protein response (UPR) in infected cells. However, it… read more here.
Keywords: viral replication; unfolded protein; protein response; infection ... See more keywords