Necrostatin-1 prevents skeletal muscle ischemia reperfusion injury by regulating Bok-mediated apoptosis
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the Chinese Medical Association"
DOI: 10.1097/jcma.0000000000000806
Abstract: Background: Receptor interacting serine/threonine kinase 1 (RIPK1) mediates apoptosis by regulating the classic proapoptotic effectors Bcl-2-associated X protein (Bax) and Bcl-2 homologous antagonist/killer (Bak). Although Bcl-2-related ovarian killer (Bok) is structurally similar to Bak and… read more here.
Keywords: regulating bok; muscle; necrostatin; bok mediated ... See more keywords
Metastability, an emerging concept governing BOK-mediated apoptosis initiation
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DOI: 10.18632/oncotarget.25801
Abstract: By regulating mitochondrial outer membrane permeabilization (MOMP), the rate-limiting event in caspase activation, BCL-2 family proteins are responsible for apoptosis initiation [1]. Most BCL-2 proteins obey canonical rules of mitochondrial apoptosis [2]. These rules define… read more here.
Keywords: bok mediated; apoptosis; apoptosis initiation; bcl ... See more keywords