Coherence of BOLD signal and electrical activity in the human brain during deep sevoflurane anesthesia
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DOI: 10.1002/brb3.679
Abstract: Changes in neural activity induce changes in functional magnetic resonance (fMRI) blood oxygenation level dependent (BOLD) signal. Commonly, increases in BOLD signal are ascribed to cellular excitation. read more here.
Keywords: electrical activity; bold signal; coherence bold; signal electrical ... See more keywords
Frequency‐dependent tACS modulation of BOLD signal during rhythmic visual stimulation
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DOI: 10.1002/hbm.23990
Abstract: Transcranial alternating current stimulation (tACS) has emerged as a promising tool for modulating cortical oscillations. In previous electroencephalogram (EEG) studies, tACS has been found to modulate brain oscillatory activity in a frequency‐specific manner. However, the… read more here.
Keywords: modulation; frequency; stimulation; rhythmic visual ... See more keywords
Altered basal forebrain BOLD signal variability at rest in posttraumatic stress disorder: A potential candidate vulnerability mechanism for neurodegeneration in PTSD
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DOI: 10.1002/hbm.25454
Abstract: Individuals with posttraumatic stress disorder (PTSD) are at increased risk for the development of various forms of dementia. Nevertheless, the neuropathological link between PTSD and neurodegeneration remains unclear. Degeneration of the human basal forebrain constitutes… read more here.
Keywords: seed; neurodegeneration; bold signal; basal forebrain ... See more keywords
A randomized, placebo-controlled, phase 1 study to evaluate the effects of TAK-063 on ketamine-induced changes in fMRI BOLD signal in healthy subjects
Sign Up to like & getrecommendations! Published in 2019 at "Psychopharmacology"
DOI: 10.1007/s00213-019-05366-1
Abstract: Rationale Phosphodiesterase 10A inhibitor TAK-063 has shown effects that suggest efficacy in schizophrenia treatment. Objective This randomized, double-blind, placebo-controlled, incomplete-crossover study investigated effects of single oral administration of TAK-063 on ketamine-induced changes in blood oxygen… read more here.
Keywords: fmri bold; ketamine induced; bold signal; placebo ... See more keywords
Effects of Ketamine and Midazolam on Simultaneous EEG/fMRI Data During Working Memory Processes.
Sign Up to like & getrecommendations! Published in 2021 at "Brain topography"
DOI: 10.1007/s10548-021-00876-8
Abstract: Reliable measures of cognitive brain activity from functional neuroimaging techniques may provide early indications of efficacy in clinical trials. Functional magnetic resonance imaging and electroencephalography provide complementary spatiotemporal information and simultaneous recording of these two… read more here.
Keywords: theta; effects ketamine; bold signal; midazolam simultaneous ... See more keywords
Creative, internally-directed cognition is associated with reduced BOLD variability
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DOI: 10.1016/j.neuroimage.2020.116758
Abstract: In a range of externally-directed tasks, intra-individual variability of fMRI BOLD signal has been shown to be a stronger predictor of cognitive performance than mean BOLD signal. BOLD variability's strong association with cognitive performance is… read more here.
Keywords: internally directed; bold variability; directed cognition; variability ... See more keywords
The coupling of BOLD signal variability and degree centrality underlies cognitive functions and psychiatric diseases
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DOI: 10.1016/j.neuroimage.2021.118187
Abstract: Brain signal variability has been consistently linked to functional integration; however, whether this coupling is associated with cognitive functions and/or psychiatric diseases has not been clarified. Using multiple multimodality datasets, including resting-state functional magnetic resonance… read more here.
Keywords: functional integration; cognitive functions; variability; bold signal ... See more keywords
Task-evoked metabolic demands of the posteromedial default mode network are shaped by dorsal attention and frontoparietal control networks
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DOI: 10.1101/2022.08.12.503715
Abstract: Although BOLD signal decreases in the default mode network (DMN) are commonly observed during attention-demanding tasks, their neurobiological underpinnings are not fully understood. Previous work has shown decreases but also increases in glucose metabolism that… read more here.
Keywords: network; glucose metabolism; mode network; bold signal ... See more keywords
Temporal fractal analysis of the rs-BOLD signal identifies brain abnormalities in autism spectrum disorder
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DOI: 10.1371/journal.pone.0190081
Abstract: Background Brain connectivity in autism spectrum disorders (ASD) has proven difficult to characterize due to the heterogeneous nature of the spectrum. Connectivity in the brain occurs in a complex, multilevel and multi-temporal manner, driving the… read more here.
Keywords: analysis; connectivity; bold signal; signal complexity ... See more keywords
Resting-state neural signal variability in women with depressive disorders
Sign Up to like & getrecommendations! Published in 2022 at "Behavioural Brain Research"
DOI: 10.2139/ssrn.4052510
Abstract: Aberrant activity and connectivity in default mode (DMN), frontoparietal (FPN), and salience (SN) network regions is well-documented in depression. Recent neuroimaging research suggests that altered variability in the blood oxygen level-dependent (BOLD) signal may disrupt… read more here.
Keywords: signal variability; depression; variability; resting state ... See more keywords
Is the Blood Oxygenation Level-Dependent fMRI Response to Motor Tasks Altered in Children After Neonatal Stroke?
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Human Neuroscience"
DOI: 10.3389/fnhum.2020.00154
Abstract: Functional MRI is increasingly being used in the assessment of brain activation and connectivity following stroke. Many of these studies rely on the Blood Oxygenation Level Dependent (BOLD) contrast. However, the stability, as well as… read more here.
Keywords: oxygenation level; level dependent; bold signal; motor ... See more keywords