Doxorubicin concentrations in bone tumour-relevant tissues after bolus and continuous infusion: a randomized porcine microdialysis study
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DOI: 10.1007/s00280-023-04637-1
Abstract: Doxorubicin is a widely used chemotherapeutic drug that can be administered intravenously as both a bolus infusion and a continuous infusion. The latter is believed to lower the risk of cardiotoxicity, which is a critical… read more here.
Keywords: infusion; tumour relevant; bolus continuous; continuous infusion ... See more keywords
Effect of repeated bolus and continuous doxorubicin administration on bone and soft tissue concentrations– a randomized study evaluated in a tumour-free porcine model
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DOI: 10.1007/s00280-025-04768-7
Abstract: The aim of this study was to evaluate plasma and bone- and soft-tissue concentrations of doxorubicin following two administrations of either bolus or continuous infusion administered at a three-week interval. The achievement of adequate concentration… read more here.
Keywords: soft tissue; tissue; bone soft; bolus continuous ... See more keywords