Articles with "bombesin" as a keyword



Towards Selective Delivery of a Ruthenium(II) Polypyridyl Complex‐Containing Bombesin Conjugate into Cancer Cells

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Published in 2022 at "ChemBioChem"

DOI: 10.1002/cbic.202200647

Abstract: An increasing number of novel Ru(II) polypyridyl complexes have been successfully applied as photosensitizers (PSs) for photodynamic therapy (PDT). Despite recent advances in optimized PSs with refined photophysical properties, the lack of tumoral selectivity is… read more here.

Keywords: cancer; polypyridyl complex; polypyridyl; towards selective ... See more keywords

Neuromedin B excites central lateral amygdala neurons and reduces cardiovascular output and fear-potentiated startle.

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Published in 2023 at "Journal of cellular physiology"

DOI: 10.1002/jcp.31020

Abstract: Neuromedin B (NMB) and gastrin-releasing peptide (GRP) are the two mammalian analogs in the bombesin peptide family that exert a variety of actions including emotional processing, appetitive behaviors, cognition, and tumor growth. The bombesin-like peptides… read more here.

Keywords: potentiated startle; amygdala; bb1 receptors; fear potentiated ... See more keywords

Evaluation of new 99mTc-labeled HYNIC-bombesin analogue for prostate cancer imaging

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Published in 2018 at "Journal of Radioanalytical and Nuclear Chemistry"

DOI: 10.1007/s10967-018-5819-z

Abstract: In this study, we introduce a new 99mTc-radiolabeled bombesin derivative for imaging of prostate cancer (PC). We used 6-hydrazinonicotinamide (HYNIC) as bi-functional chelating agent and tricine/ethylenediamine diacetic acid (EDDA) as an exchange co-ligands. Radiolabeling was achieved… read more here.

Keywords: bombesin; evaluation new; new 99mtc; prostate cancer ... See more keywords

Bombesin administration impairs memory and does not reverse memory deficit caused by sleep deprivation

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Published in 2017 at "Behavioural Brain Research"

DOI: 10.1016/j.bbr.2017.05.027

Abstract: HighlightsBombesin impairs consolidation, but not acquisition or evocation of emotional memory.Sleep deprivation impairs the performance of rats in the aversive memory task.Bombesin do not improve aversive memory task impairment by sleep deprivation. Abstract Sleep deprivation… read more here.

Keywords: administration; sleep deprivation; bombesin; deficit ... See more keywords

Discovery and functional characterization of a bombesin-type neuropeptide signaling system in an invertebrate

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Published in 2025 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2420966122

Abstract: Significance The peptide bombesin (BN) was first discovered in frog skin and subsequently the BN-related neuropeptides gastrin-releasing peptide and neuromedin B were identified in mammals and other vertebrates as regulators of feeding, digestion, and other… read more here.

Keywords: signaling system; type; discovery functional; bombesin ... See more keywords