Towards Selective Delivery of a Ruthenium(II) Polypyridyl Complex‐Containing Bombesin Conjugate into Cancer Cells
Sign Up to like & getrecommendations! Published in 2022 at "ChemBioChem"
DOI: 10.1002/cbic.202200647
Abstract: An increasing number of novel Ru(II) polypyridyl complexes have been successfully applied as photosensitizers (PSs) for photodynamic therapy (PDT). Despite recent advances in optimized PSs with refined photophysical properties, the lack of tumoral selectivity is… read more here.
Keywords: cancer; polypyridyl complex; polypyridyl; towards selective ... See more keywords
Neuromedin B excites central lateral amygdala neurons and reduces cardiovascular output and fear-potentiated startle.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of cellular physiology"
DOI: 10.1002/jcp.31020
Abstract: Neuromedin B (NMB) and gastrin-releasing peptide (GRP) are the two mammalian analogs in the bombesin peptide family that exert a variety of actions including emotional processing, appetitive behaviors, cognition, and tumor growth. The bombesin-like peptides… read more here.
Keywords: potentiated startle; amygdala; bb1 receptors; fear potentiated ... See more keywords
Evaluation of new 99mTc-labeled HYNIC-bombesin analogue for prostate cancer imaging
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Radioanalytical and Nuclear Chemistry"
DOI: 10.1007/s10967-018-5819-z
Abstract: In this study, we introduce a new 99mTc-radiolabeled bombesin derivative for imaging of prostate cancer (PC). We used 6-hydrazinonicotinamide (HYNIC) as bi-functional chelating agent and tricine/ethylenediamine diacetic acid (EDDA) as an exchange co-ligands. Radiolabeling was achieved… read more here.
Keywords: bombesin; evaluation new; new 99mtc; prostate cancer ... See more keywords
Bombesin administration impairs memory and does not reverse memory deficit caused by sleep deprivation
Sign Up to like & getrecommendations! Published in 2017 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2017.05.027
Abstract: HighlightsBombesin impairs consolidation, but not acquisition or evocation of emotional memory.Sleep deprivation impairs the performance of rats in the aversive memory task.Bombesin do not improve aversive memory task impairment by sleep deprivation. Abstract Sleep deprivation… read more here.
Keywords: administration; sleep deprivation; bombesin; deficit ... See more keywords