Unveiling the role of BON domain-containing proteins in antibiotic resistance
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2024.1518045
Abstract: The alarming rise of antibiotic-resistant Gram-negative bacteria poses a global health crisis. Their unique outer membrane restricts antibiotic access. While diffusion porins are well-studied, the role of BON domain-containing proteins (BDCPs) in resistance remains unexplored.… read more here.
Keywords: resistance; domain; domain containing; containing proteins ... See more keywords
Structure of dual BON-domain protein DolP identifies phospholipid binding as a new mechanism for protein localisation
Sign Up to like & getrecommendations! Published in 2020 at "eLife"
DOI: 10.7554/elife.62614
Abstract: The Gram-negative outer-membrane envelops the bacterium and functions as a permeability barrier against antibiotics, detergents, and environmental stresses. Some virulence factors serve to maintain the integrity of the outer membrane, including DolP (formerly YraP) a… read more here.
Keywords: localisation; structure; dolp; bon domain ... See more keywords