Substance P in Solution: Trans-to-Cis Configurational Changes of Penultimate Prolines Initiate Non-enzymatic Peptide Bond Cleavages
Sign Up to like & getrecommendations! Published in 2019 at "Journal of The American Society for Mass Spectrometry"
DOI: 10.1007/s13361-019-02159-w
Abstract: AbstractWe report ion mobility spectrometry and mass spectrometry studies of the non-enzymatic step-by-step degradation of substance P (subP), an 11-residue neuropeptide, with the sequence Arg1-Pro2-Lys3-Pro4-Gln5-Gln6-Phe7-Phe8-Gly9-Leu10-Met11-NH2, in ethanol. At elevated solution temperatures (55 to 75 °C),… read more here.
Keywords: bond; trans cis; peptide bond; non enzymatic ... See more keywords
C-C Bond Cleavages of Cyclopropenes: Operating for Selective Ring-Opening Reactions.
Sign Up to like & getrecommendations! Published in 2020 at "Chemical reviews"
DOI: 10.1021/acs.chemrev.0c00151
Abstract: This review highlights key reactivities relying on C-C bond cleavages of cyclopropenes. Metal-catalyzed and metal-free transformations are covered in reactions involving direct ring-opening processes or transformations through nonisolable cyclopropane intermediates generated from cyclopropenes. Special emphasis… read more here.
Keywords: ring opening; bond cleavages; cleavages cyclopropenes; cyclopropenes operating ... See more keywords
H–H and N–H Bond Cleavages of Dihydrogen and Ammonia by a Bifunctional Imido (NH)-Bridged Diiridium Complex: A DFT Study
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DOI: 10.1021/acs.organomet.7b00581
Abstract: The mechanisms of H–H and N–H bond cleavages of dihydrogen and ammonia mediated by the diiridium μ2-imido complex [(Cp*Ir)2(μ2-H)(μ2-NH)]+ (A; Cp* = η5-C5Me5) were theoretically investigated with the density functional theory (DFT) method. Both oxidative… read more here.
Keywords: imido; bond; dihydrogen ammonia; cleavages dihydrogen ... See more keywords