TCR–pMHC bond conformation controls TCR ligand discrimination
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DOI: 10.1038/s41423-019-0273-6
Abstract: A major unanswered question is how a TCR discriminates between foreign and self-peptides presented on the APC surface. Here, we used in situ fluorescence resonance energy transfer (FRET) to measure the distances of single TCR–pMHC… read more here.
Keywords: bond; bond conformation; tcr pmhc; tcr ... See more keywords