TBAB-Catalyzed Csp 3 -N Bond Formation by Coupling Pyridotriazoles with Anilines: A New Route to (2-Pyridyl)alkylamines
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.201801803
Abstract: A new metal-free procedure allowing a Csp 3-N bond formation through coupling of pyridotriazoles and weakly nucleophilic anilines has been developed. This sustainable reaction shows high tolerance towards functional groups (ketones, free alcohols) leading to… read more here.
Keywords: coupling pyridotriazoles; csp bond; bond formation; formation ... See more keywords
2,2′‐Dipyridyl diselenide: A chemoselective tool for cysteine deprotection and disulfide bond formation
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Peptide Science"
DOI: 10.1002/psc.3236
Abstract: There are many examples of bioactive, disulfide‐rich peptides and proteins whose biological activity relies on proper disulfide connectivity. Regioselective disulfide bond formation is a strategy for the synthesis of these bioactive peptides, but many of… read more here.
Keywords: cys; disulfide bond; bond formation; formation ... See more keywords
Uncatalyzed peptide bond formation between two double amino acid molecules in the gas phase
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Quantum Chemistry"
DOI: 10.1002/qua.25435
Abstract: The gas phase mechanism for peptide bond formation between two double amino acid (DAA) molecules ((NH2)2C(COOH)2) is investigated in the absence of any catalysts. Two different paths, concerted and stepwise, each leading to both cis… read more here.
Keywords: bond; gas phase; peptide bond; bond formation ... See more keywords
Water-assisted peptide bond formation between two double amino acid molecules in the gas phase
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Modeling"
DOI: 10.1007/s00894-019-4081-9
Abstract: The gas phase mechanism of the peptide bond formation between two double amino acid (DAA) molecules described by the (NH2)2C(COOH)2 formula is investigated in the presence of a water molecule. Formations of trans and cis… read more here.
Keywords: bond formation; water; formation two; peptide bond ... See more keywords
Lemon juice catalyzed C–C bond formation via C–H activation of methylarene: a sustainable synthesis of chromenopyrimidines
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Diversity"
DOI: 10.1007/s11030-019-09980-1
Abstract: Abstract An economical and proficient approach has been developed for the synthesis of chromenopyrimidines via three-component reaction of thiobarbituric acid/barbituric acid, methylarenes and dimedone/1,3-cyclohexanedione by using lemon juice as a natural, biodegradable catalyst and TBHP… read more here.
Keywords: formation via; lemon juice; bond formation; synthesis chromenopyrimidines ... See more keywords
Csp3–N bond formation in aminothiophenes by 1,1-dibromo isocyanide: the unexpected 1,5-binucleophilicity of substrates
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the Iranian Chemical Society"
DOI: 10.1007/s13738-017-1195-9
Abstract: The N-cyclohexylcarbonimidoyl dibromide in situ, generated by cyclohexylisocyanide and bromine in reaction with several deactivated 5-acetyl-4-amino-2-methylsulfanyl-3-carbonitrile, appears as a cyclohexyl transformer to the substrate via Csp3–N bond formation without using any base or catalyst at… read more here.
Keywords: formation aminothiophenes; bond formation; reaction; csp3 bond ... See more keywords
Cysteine mediated disulfide bond formation in RAGE V domain facilitates its functionally relevant dimerization.
Sign Up to like & getrecommendations! Published in 2018 at "Biochimie"
DOI: 10.1016/j.biochi.2018.07.024
Abstract: Receptor for Advanced Glycation End product (RAGE) is a multiligand receptor implicated in diverse pathological conditions such as diabetes, atherosclerosis, cancer and neural diseases. Extracellular, RAGE consists of V, C1 and C2 domains. Here, we… read more here.
Keywords: disulfide bond; mediated disulfide; bond formation; rage ... See more keywords
Synthesis of 1,4-dihydropyrazolo[4,3-b]indoles via intramolecular C(sp2)-N bond formation involving nitrene insertion, DFT study and their anticancer assessment.
Sign Up to like & getrecommendations! Published in 2021 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2021.105114
Abstract: We herein report a new synthetic route for a series of unreported 1,4-dihydropyrazolo[4,3-b]indoles (6-8) via deoxygenation of o-nitrophenyl-substituted N-aryl pyrazoles and subsequent intramolecular (sp2)-N bond formation under microwave irradiation expedite modified Cadogan condition. This method… read more here.
Keywords: bond formation; intramolecular sp2; indoles via; dft study ... See more keywords
First-principle investigation on catalytic hydrogenation of benzaldehyde over Pt-group metals
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DOI: 10.1016/j.cattod.2020.07.039
Abstract: Abstract Understanding the hydrogenation of organic compounds in the aqueous phase has always been fundamentally important for improving carbon neutral pathways to fuels and value-added chemicals. In this study, we investigated both thermodynamic and kinetic… read more here.
Keywords: first principle; benzaldehyde; bond formation; principle investigation ... See more keywords
The first carbon-carbon bond formation mechanism in methanol-to-hydrocarbons process over chabazite zeolite
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DOI: 10.1016/j.chempr.2021.05.023
Abstract: Summary The first C–C bond formation mechanism in the methanol-to-hydrocarbons (MTH) process has always been a highly controversial issue. Using solid-state NMR spectroscopy, the initial C1 reactants and C1 intermediates were observed on the HSSZ-13… read more here.
Keywords: carbon; bond formation; zeolite; bond ... See more keywords
Enzymatic N N bond formation: Mechanism for the N-nitroso synthesis catalyzed by non-heme iron SznF enzyme
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Catalysis"
DOI: 10.1016/j.jcat.2021.04.010
Abstract: Abstract Enzymatic N-N bond formation is rare. Herein, the mechanism for the N-nitrosation from Nδ-hydroxy-Nω-hydroxy-Nω-methyl-L-arginine (L-HMA) catalyzed by SznF, a non-heme iron enzyme, has been illustrated, using density functional calculations. The reaction proceeds through the… read more here.
Keywords: bond formation; non heme; enzymatic bond; bond ... See more keywords