Integrin Catch Bond Kinetics Mediate Mechanosensing during Cell Spreading
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2016.11.189
Abstract: Cell spreading and polarization are morphogenetic responses to extracellular matrix adhesion. Cultured fibroblasts polarize when plated on rigid, but not compliant substrates. In this study, we demonstrate that fibroblasts have increased spread area on compliant… read more here.
Keywords: bond kinetics; integrin catch; catch bond; cell spreading ... See more keywords
Flow driven vesicle unbinding under mechanosensitive adhesion.
Sign Up to like & getrecommendations! Published in 2022 at "Soft matter"
DOI: 10.1039/d1sm01284c
Abstract: Ligand receptor based adhesion is the primary mode of interaction of cellular blood constituents with the endothelium. These adhered entities also experience shear flow imposed by the blood which may lead to their detachment due… read more here.
Keywords: adhesion; ligand receptor; flow; bond kinetics ... See more keywords