Hydrogen-Bonding Controlled Nickel-Catalyzed Regioselective Cyclotrimerization of Terminal Alkynes.
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DOI: 10.1021/acs.orglett.1c01095
Abstract: Herein we report a hydrogen-bonding controlled nickel-catalyzed regioselective cyclotrimerization of terminal alkynes in moderate to excellent yields with high regioselectivities toward 1,3,5-trisubstituted benzenes. This method features a cheap catalyst, mild reaction conditions, and excellent functional… read more here.
Keywords: controlled nickel; bonding controlled; terminal alkynes; hydrogen bonding ... See more keywords