Revisiting the halogen bonding between phosphodiesterase type 5 and its inhibitors
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DOI: 10.1007/s00894-018-3897-z
Abstract: Halogenated ligands are nowadays commonly designed in order to increase their potency against protein targets. Although novel computational methods of evaluating the affinity of such halogenated inhibitors have emerged, they still lack the sufficient accuracy,… read more here.
Keywords: phosphodiesterase type; halogen bonding; bonding phosphodiesterase; type inhibitors ... See more keywords