Influence of Metastatic Bone Lesion Type and Tumor Origin on Human Vertebral Bone Architecture, Matrix Quality, and Mechanical Properties
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DOI: 10.1002/jbmr.4539
Abstract: Metastatic spine disease is incurable, causing increased vertebral fracture risk and severe patient morbidity. Here, we demonstrate that osteolytic, osteosclerotic, and mixed bone metastasis uniquely modify human vertebral bone architecture and quality, affecting vertebral strength… read more here.
Keywords: bone architecture; vertebral strength; bone; human vertebral ... See more keywords
Impaired Bone Architecture in Peripubertal Children With HIV, Despite Treatment With Antiretroviral Therapy: A Cross‐Sectional Study From Zimbabwe
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DOI: 10.1002/jbmr.4752
Abstract: HIV infection has multi‐system adverse effects in children, including on the growing skeleton. We aimed to determine the association between chronic HIV infection and bone architecture (density, size, strength) in peripubertal children. We conducted a… read more here.
Keywords: bone architecture; hiv; peripubertal children; bone ... See more keywords
Age-Dependent Changes in Bone Architecture, Patterning, and Biomechanics During Skeletal Regeneration
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DOI: 10.3389/fcell.2021.749055
Abstract: Mouse digit amputation provides a useful model of bone growth after injury, in that the injury promotes intramembranous bone formation in an adult animal. The digit tip is composed of skin, nerves, blood vessels, bones,… read more here.
Keywords: biomechanics; regeneration; bone; changes bone ... See more keywords