Inhibition of Sympathetic Activation by Delivering Calcium Channel Blockers from a 3D Printed Scaffold to Promote Bone Defect Repair
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202200785
Abstract: Enhancing osteogenesis by promoting neural network reconstruction and neuropeptide release is considered to be an attractive strategy for repairing of critical size bone defects. However, traumatic bone defects often activate the damaged sympathetic nervous system… read more here.
Keywords: calcium; bone; bone defect; activation ... See more keywords
Zinc-based Tannin-modified Composite Microparticulate Scaffolds with Balanced Antimicrobial Activity and Osteogenesis for Infected Bone Defect Repair.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202300303
Abstract: Treatment of infected bone defects is a major clinical challenge, bioactive materials combining sufficient antimicrobial activity and favorable osteogenic ability are urgently needed. In this study, through a facile one-pot hydrothermal reaction of zinc acetate… read more here.
Keywords: bone; activity; bone defect; infected bone ... See more keywords
Dual Biosignal-Functional Injectable Microspheres for Remodeling Osteogenic Microenvironment.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202201656
Abstract: Bone defect regeneration depends on the population and lifespan of M2 macrophages, which are regulated by dual signals generated by the "physical" spatial configuration of biological tissues and "molecular" chemokines. Herein, inspired by the reprogramming… read more here.
Keywords: biosignal functional; plla; bone defect; plla microspheres ... See more keywords
Octacalcium phosphate collagen composite facilitates bone regeneration of large mandibular bone defect in humans
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.2110
Abstract: Recently it was reported that the implantation of octacalcium phosphate (OCP) and collagen composite (OCP–collagen) was effective at promoting bone healing in small bone defects after cystectomy in humans. In addition, OCP–collagen promoted bone regeneration… read more here.
Keywords: collagen; bone defect; ocp collagen; bone ... See more keywords
Fabrication of BMP‐2‐peptide–Deferoxamine‐ and QK‐peptide‐functionalized nanoscaffolds and their application for bone defect treatment
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.3364
Abstract: The microenvironment in the healing process of large bone defects requires suitable conditions to promote osteogenesis and angiogenesis. Coaxial electrospinning is a mature method in bone tissue engineering (BTE) and allows functional modification. Appropriate modification… read more here.
Keywords: bone; microscopy; bmp peptide; bone defect ... See more keywords
Arthroscopic remplissage with all-suture anchors causes cystic lesions in the humerus: a volumetric CT study of 55 anchors
Sign Up to like & getrecommendations! Published in 2020 at "Knee Surgery, Sports Traumatology, Arthroscopy"
DOI: 10.1007/s00167-020-06314-9
Abstract: Purpose To evaluate with computed tomography (CT) the incidence of implant-related osteolysis after implantation of two types of all-suture anchors during remplissage for the management of Hill-Sachs lesions in shoulder instability. Methods Single-cohort, observational study… read more here.
Keywords: volume; suture anchors; bone defect; arthroscopic remplissage ... See more keywords
Bone morphogenetic protein 2-induced cellular chemotaxis drives tissue patterning during critical-sized bone defect healing: an in silico study
Sign Up to like & getrecommendations! Published in 2021 at "Biomechanics and Modeling in Mechanobiology"
DOI: 10.1007/s10237-021-01466-0
Abstract: Critical-sized bone defects are critical healing conditions that, if left untreated, often lead to non-unions. To reduce the risk, critical-sized bone defects are often treated with recombinant human BMP-2. Although enhanced bone tissue formation is… read more here.
Keywords: tissue patterning; bmp; bone defect; critical sized ... See more keywords
An innovative strategy to treat large metaphyseal segmental femoral bone defect using customized design and 3D printed micro-porous prosthesis: a prospective clinical study
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Materials Science: Materials in Medicine"
DOI: 10.1007/s10856-020-06406-5
Abstract: Five patients with segmental irregular-shaped bone defect of the femur were recruited in this study from 2017.12 to 2018.11. All patients were treated by customized design and 3D printed micro-porous prosthesis. And the procedure was… read more here.
Keywords: printed micro; bone defect; customized design; bone ... See more keywords
Comparison Capacity of Collagen Hydrogel and Collagen/Strontium Bioglass Nanocomposite Scaffolds With and Without mesenchymal Stem Cells in Regeneration of Critical Sized Bone Defect in a Rabbit Animal Model.
Sign Up to like & getrecommendations! Published in 2021 at "Biological trace element research"
DOI: 10.1007/s12011-021-02909-6
Abstract: Bone self-healing is limited and requires additional or external intervention to promote and accelerate bone regeneration. Therefore, the aim of this study was to investigate the potential capacity of hydrogel collagen (Co) nanocomposite alone, and… read more here.
Keywords: collagen; hydrogel; bone defect; regeneration ... See more keywords
Performance of two bone substitutes of novel cotton-like β-TCP/PDLGA and granular β-TCP on bone regeneration in the femoral bone defect of the Beagle dogs
Sign Up to like & getrecommendations! Published in 2020 at "Bone Reports"
DOI: 10.1016/j.bonr.2020.100718
Abstract: This study aimed to clarify whether novel cotton-like composite made of β-tricalcium phosphate (β-TCP) and poly(Dl-lactide-co-glycolide) (PDLGA) has a different effect on in vivo bone regeneration after bone defect than that of granular β-TCP. Five… read more here.
Keywords: tcp; bone; bone defect; tcp pdlga ... See more keywords
Nature-Inspired Multifunctional Bilayer Architecture Advances Bone Defect Repair
Sign Up to like & getrecommendations! Published in 2019 at "Chem"
DOI: 10.1016/j.chempr.2019.09.004
Abstract: Construction of multifunctional guided bone regeneration (GBR) membranes is critical to clinical bone defect repair but still remains challenging. Recently in Matter, Yu and co-workers reported a multifunctional bilayer nanocomposite GBR membrane with most ideal… read more here.
Keywords: bone; bone defect; multifunctional bilayer; defect repair ... See more keywords