Bone-Derived dECM Hydrogels Support Tunable Microenvironments for In Vitro Osteogenic Differentiation.
Sign Up to like & getrecommendations! Published in 2025 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202501350
Abstract: Decellularized extracellular matrix (dECM)‐based biomaterials mimic native ECM and support 3D cell culture. A photocrosslinkable porcine bone‐derived dECM hydrogel (dECM‐MA) is developed with tunable mechanical properties for tissue‐specific in vitro models. Trabecular bone is demineralized… read more here.
Keywords: bone derived; culture; derived decm; decm ... See more keywords
Effect of long‐term heat exposure on rheological and intrinsic water characteristics of bone‐derived beef stocks
Sign Up to like & getrecommendations! Published in 2019 at "Magnetic Resonance in Chemistry"
DOI: 10.1002/mrc.4831
Abstract: Bone‐derived protein stocks are used in food industry to enhance taste of soups, sauces, and a range of other products. Both during commercial manufacturing and when used for culinary purposes, the stocks may be exposed… read more here.
Keywords: heat; beef stocks; bone derived; heat exposure ... See more keywords
Three‐dimensional environment and vascularization induce osteogenic maturation of human adipose‐derived stem cells comparable to that of bone‐derived progenitors
Sign Up to like & getrecommendations! Published in 2020 at "Stem Cells Translational Medicine"
DOI: 10.1002/sctm.19-0207
Abstract: While human adipose‐derived stem cells (hADSCs) are known to possess osteogenic differentiation potential, the bone tissues formed are generally considered rudimentary and immature compared with those made by bone‐derived precursor cells such as human bone… read more here.
Keywords: vascularization; osteogenic maturation; bone; bone derived ... See more keywords
Associations between circulating bone-derived hormones lipocalin 2, osteocalcin, and glucose metabolism in acromegaly
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Endocrinological Investigation"
DOI: 10.1007/s40618-020-01221-9
Abstract: Purpose The aim was to examine changes in the bone-derived hormone lipocalin 2 (LCN2) levels in patients with active acromegaly and to investigate the potential roles of LCN2 and osteocalcin in glucose metabolism. Methods We… read more here.
Keywords: lcn2; glucose metabolism; osteocalcin glucose; bone derived ... See more keywords
Jagged1 promotes mineralization in human bone-derived cells.
Sign Up to like & getrecommendations! Published in 2019 at "Archives of oral biology"
DOI: 10.1016/j.archoralbio.2019.01.013
Abstract: OBJECTIVES The present study aimed to investigate the expression of Notch signaling components during osteogenic differentiation in vitro and bone healing in vivo. In addition, the influence of Notch signaling on osteogenic differentiation of human… read more here.
Keywords: human bone; bone; expression; bone derived ... See more keywords
The endocrine role of bone: Novel functions of bone-derived cytokines.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2020.114308
Abstract: Bone-derived cytokines refer to various proteins and peptides that are released from the skeleton and can distribute in organisms to regulate homeostasis by targeting many organs, such as the pancreas, brain, testicles, and kidneys. In… read more here.
Keywords: endocrine role; role bone; bone novel; bone ... See more keywords
BoneMA—synthesis and characterization of a methacrylated bone-derived hydrogel for bioprinting of in-vitro vascularized tissue constructs
Sign Up to like & getrecommendations! Published in 2020 at "Biofabrication"
DOI: 10.1088/1758-5090/abb11f
Abstract: It has long been proposed that recapitulating the extracellular matrix (ECM) of native human tissues in the laboratory may enhance the regenerative capacity of engineered scaffolds in-vivo. Organ- and tissue-derived decellularized ECM biomaterials have been… read more here.
Keywords: hydrogel bioprinting; matrix; tissue; bone ... See more keywords
NLRP3 and AIM2 inflammasomes expression is modified by LPS and titanium ions increasing the release of active IL-1β in alveolar bone-derived MSCs
Sign Up to like & getrecommendations! Published in 2024 at "Stem Cells Translational Medicine"
DOI: 10.1093/stcltm/szae042
Abstract: Abstract Periodontitis and peri-implantitis are inflammatory diseases of infectious etiology that lead to the destruction of the supporting tissues located around teeth or implants. Although both pathologies share several characteristics, it is also known that… read more here.
Keywords: inflammatory process; nlrp3 aim2; titanium ions; bone derived ... See more keywords
Constitutively activated AMPKα1 protects against skeletal aging in mice by promoting bone-derived IGF-1 secretion.
Sign Up to like & getrecommendations! Published in 2023 at "Cell proliferation"
DOI: 10.1111/cpr.13476
Abstract: Senile osteoporosis is characterized by age-related bone loss and bone microarchitecture deterioration. However, little is known to date about the mechanism that maintains bone homeostasis during aging. In this study, we identify adenosine monophosphate-activated protein… read more here.
Keywords: igf secretion; bone; promoting bone; skeletal aging ... See more keywords
The roles of bone‐derived exosomes and exosomal microRNAs in regulating bone remodelling
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.13039
Abstract: Pathological destructive bone diseases are primarily caused by the failure of a lifelong self‐renewal process of the skeletal system called bone remodelling. The mechanisms underlying this process include enhanced osteoclast activity and decreased generation of… read more here.
Keywords: bone remodelling; bone; bone derived; exosomes exosomal ... See more keywords
The Emerging Role of Bone-Derived Hormones in Diabetes Mellitus and Diabetic Kidney Disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.938830
Abstract: Diabetic kidney disease (DKD) causes the greatest proportion of end-stage renal disease (ESRD)–related mortality and has become a high concern in patients with diabetes mellitus (DM). Bone is considered an endocrine organ, playing an emerging… read more here.
Keywords: role; disease; derived hormones; bone derived ... See more keywords