The Actions of IGF-1 in the Growth Plate and Its Role in Postnatal Bone Elongation
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DOI: 10.1007/s11914-020-00570-x
Abstract: Purpose of Review Bone elongation is a complex process driven by multiple intrinsic (hormones, growth factors) and extrinsic (nutrition, environment) variables. Bones grow in length by endochondral ossification in cartilaginous growth plates at ends of… read more here.
Keywords: bone elongation; bone; actions igf; growth ... See more keywords
Osteolectin increases bone elongation and body length by promoting growth plate chondrocyte proliferation
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2220159120
Abstract: Significance Osteolectin promotes the maintenance of bone mass in adult mice, but there has not been genetic evidence that Osteolectin is functionally important in humans. In the current study, we identified a function for Osteolectin… read more here.
Keywords: growth plate; chondrocyte proliferation; plate chondrocyte; bone elongation ... See more keywords