LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "bone formation" as a keyword



Indoxyl sulfate, a uremic toxin in chronic kidney disease, suppresses both bone formation and bone resorption

Sign Up to like & get
recommendations! Published in 2017 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.12258

Abstract: Abnormalities of bone turnover are commonly observed in patients with chronic kidney disease (CKD), and the low‐turnover bone disease is considered to be associated with low serum parathyroid hormone (PTH) levels and skeletal resistance to… read more here.

Keywords: bone formation; turnover; bone resorption; disease ... See more keywords

Growth‐Factor Free Multicomponent Nanocomposite Hydrogels That Stimulate Bone Formation

Sign Up to like & get
recommendations! Published in 2020 at "Advanced Functional Materials"

DOI: 10.1002/adfm.201906205

Abstract: Synthetic osteo‐promoting materials that are able to stimulate and accelerate bone formation without the addition of exogenous cells or growth factors represent a major opportunity for an aging world population. A co‐assembling system that integrates… read more here.

Keywords: growth factor; bone formation; multicomponent; formation ... See more keywords
Photo by ldxcreative from unsplash

Hypoxia Drives Material‐Induced Heterotopic Bone Formation by Enhancing Osteoclastogenesis via M2/Lipid‐Loaded Macrophage Axis

Sign Up to like & get
recommendations! Published in 2023 at "Advanced Science"

DOI: 10.1002/advs.202207224

Abstract: Heterotopic ossification (HO) is a double‐edged sword. Pathological HO presents as an undesired clinical complication, whereas controlled heterotopic bone formation by synthetic osteoinductive materials shows promising therapeutic potentials for bone regeneration. However, the mechanism of… read more here.

Keywords: bone formation; heterotopic bone; material induced; hypoxia ... See more keywords

The Sirt1‐Piezo1 Axis Promotes Bone Formation and Repair in Mice

Sign Up to like & get
recommendations! Published in 2025 at "Advanced Science"

DOI: 10.1002/advs.202510103

Abstract: The mechanosensitive Piezo1 channel protein plays a pivotal role in promoting bone formation and repair; however, its underlying molecular mechanism(s) are poorly defined. Here this study shows that Sirt1 positively regulates Piezo1 expression and activity… read more here.

Keywords: repair; formation repair; bone formation; sirt1 ... See more keywords

Culture system for longitudinal monitoring of bone dynamics ex vivo

Sign Up to like & get
recommendations! Published in 2024 at "Biotechnology and Bioengineering"

DOI: 10.1002/bit.28848

Abstract: To quantify and visualize both bone formation and resorption within osteochondral explants cultured ex vivo is challenging with the current analysis techniques. An approach that enables monitoring of bone remodeling dynamics is longitudinal microcomputed tomography… read more here.

Keywords: culture; culture system; bone formation; bone ... See more keywords

SIRT1/Notch1 signal axis involves in the promoting effect of Segetalin B on bone formation

Sign Up to like & get
recommendations! Published in 2022 at "Drug Development Research"

DOI: 10.1002/ddr.22001

Abstract: Phytoestrogens are a class of potential natural medicines for treating postmenopausal osteoporosis (PMOP). Segetalin B (SB) is a cyclic peptide compound showing estrogenic activity. This study reports the effect of SB on bone formation among… read more here.

Keywords: bone formation; ovx rats; effect; bone ... See more keywords

Bone Formation Is Coupled to Resorption Via Suppression of Sclerostin Expression by Osteoclasts

Sign Up to like & get
recommendations! Published in 2017 at "Journal of Bone and Mineral Research"

DOI: 10.1002/jbmr.3175

Abstract: Bone formation is coupled to bone resorption throughout life. However, the coupling mechanisms are not fully elucidated. Using Tnfrsf11b‐deficient (OPG–/–) mice, in which bone formation is clearly coupled to bone resorption, we found here that… read more here.

Keywords: sclerostin expression; bone formation; bone; expression ... See more keywords

Overexpression of MiR‐335‐5p Promotes Bone Formation and Regeneration in Mice

Sign Up to like & get
recommendations! Published in 2017 at "Journal of Bone and Mineral Research"

DOI: 10.1002/jbmr.3230

Abstract: MicroRNAs (miRNAs) and the Wnt signaling pathway play critical roles in regulating bone development and homeostasis. Our previous study revealed high expression of miR‐335‐5p in osteoblasts and hypertrophic chondrocytes in mouse embryos and the ability… read more here.

Keywords: bone; mir 335; transgenic mice; bone formation ... See more keywords
Photo by sammoqadam from unsplash

Discoidin Receptor 2 Controls Bone Formation and Marrow Adipogenesis

Sign Up to like & get
recommendations! Published in 2018 at "Journal of Bone and Mineral Research"

DOI: 10.1002/jbmr.3534

Abstract: The authors notified the editors of JBMR about a possible duplication (in reverse orientation) of the T-ERK panel from Fig. 1A in an article in the Journal of Biological Chemistry (1) and in Fig. 5B… read more here.

Keywords: formation marrow; receptor controls; controls bone; discoidin receptor ... See more keywords

A Novel Rhein Derivative Modulates Bone Formation and Resorption and Ameliorates Estrogen‐Dependent Bone Loss

Sign Up to like & get
recommendations! Published in 2019 at "Journal of Bone and Mineral Research"

DOI: 10.1002/jbmr.3604

Abstract: Osteoporosis, an osteolytic disease that affects millions of people worldwide, features a bone remodeling imbalance between bone resorption by osteoclasts and bone formation by osteoblasts. Identifying dual target‐directed agents that inhibit excessive bone resorption and… read more here.

Keywords: bone; bone formation; bone loss; resorption ... See more keywords

VEGFA From Early Osteoblast Lineage Cells (Osterix+) Is Required in Mice for Fracture Healing

Sign Up to like & get
recommendations! Published in 2019 at "Journal of Bone and Mineral Research"

DOI: 10.1002/jbmr.3755

Abstract: Bone formation via intramembranous and endochondral ossification is necessary for successful healing after a wide range of bone injuries. The pleiotropic cytokine, vascular endothelial growth factor A (VEGFA) has been shown, via nonspecific pharmacologic inhibition,… read more here.

Keywords: angiogenesis; fracture; bone formation; bone ... See more keywords