Traditional and Non-traditional Risk Factors for Osteoporosis in CKD.
Sign Up to like & getrecommendations! Published in 2021 at "Calcified tissue international"
DOI: 10.1007/s00223-020-00786-0
Abstract: Osteoporosis is a state of bone fragility with reduced skeletal resistance to trauma, and consequently increased risk of fracture. A wide range of conditions, including traditional risk factors, lifestyle choices, diseases and their treatments may… read more here.
Keywords: bone fragility; risk; risk factors; traditional risk ... See more keywords
Falls and Fractures in Diabetes—More than Bone Fragility
Sign Up to like & getrecommendations! Published in 2019 at "Current Osteoporosis Reports"
DOI: 10.1007/s11914-019-00513-1
Abstract: Purpose of ReviewBased on a systematic literature search, we performed a comprehensive review of risk factors for falls and fractures in patients with diabetes.Recent FindingsPatients with diabetes have an increased risk of fractures partly explained… read more here.
Keywords: risk; falls fractures; fractures diabetes; bone fragility ... See more keywords
LOX-related collagen crosslink changes act as an initiator of bone fragility in a ZDF rats model.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.11.082
Abstract: Diabetes mellitus type 2 (DM2) results in bone abnormalities that manifest as increased bone fragility. Bone consists of two phases, the mineral phase and the matrix phase, and disorders in both are seen in DM2.… read more here.
Keywords: fragility; post yield; bone fragility; insoluble collagen ... See more keywords
New technologies in the evaluation of bone fragility and its application in Endocrinology.
Sign Up to like & getrecommendations! Published in 2020 at "Endocrinologia, diabetes y nutricion"
DOI: 10.1016/j.endinu.2020.01.005
Abstract: Bone mineral density using dual-energy X-ray absorptiometry is the gold standard for the assessment of bone and an important predictor of fracture risk. However, most fragility fractures occur in people without densitometric osteoporosis, especially in… read more here.
Keywords: technologies evaluation; endocrinology; bone fragility; bone ... See more keywords
Molecular Abnormalities Underlying Bone Fragility in Chronic Kidney Disease
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DOI: 10.1155/2017/3485785
Abstract: Prevention of bone fractures is one goal of therapy for patients with chronic kidney disease-mineral and bone disorder (CKD-MBD), as indicated by the Kidney Disease: Improving Global Outcomes guidelines. CKD patients, including those on hemodialysis,… read more here.
Keywords: bone; bone fragility; kidney disease;
Outcomes of Zoledronic Acid Use in Paediatric Conditions
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DOI: 10.1159/000512730
Abstract: Introduction: Limited evidence is available concerning experience with use of zoledronic acid (ZA) and treatment for conditions other than primary bone fragility. Materials and Methods: A retrospective review of all Royal Children Hospital patients who… read more here.
Keywords: zoledronic acid; bone; bone fragility; use paediatric ... See more keywords
High-fat and high-carbohydrate diets increase bone fragility through TGF-β–dependent control of osteocyte function
Sign Up to like & getrecommendations! Published in 2024 at "JCI Insight"
DOI: 10.1172/jci.insight.175103
Abstract: Obesity can increase the risk of bone fragility, even when bone mass is intact. This fragility stems from poor bone quality, potentially caused by deficiencies in bone matrix material properties. However, cellular and molecular mechanisms… read more here.
Keywords: bone fragility; high carbohydrate; high fat;
Effects of Prolonged Proton-Pump Inhibitor Use on Renal Dysfunction and Bone Fragility
Sign Up to like & getrecommendations! Published in 2024 at "Annals of Pharmacotherapy"
DOI: 10.1177/10600280241273773
Abstract: Background: Proton-pump inhibitor (PPI) use for management of gastroesophageal reflux disease (GERD) consists of a short-duration trial, according to guidelines. Long-term usage is appropriate under certain indications. Literature has increasingly documented an adverse effect profile… read more here.
Keywords: pump inhibitor; proton pump; ppi; ppi use ... See more keywords
Lower incidence of fracture after IV bisphosphonates in girls with Rett syndrome and severe bone fragility
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DOI: 10.1371/journal.pone.0186941
Abstract: Background Classic Rett Syndrome (RS) is a disabling condition mainly caused by MECP2 mutations. Girls with RS are at risk of developing bone fragility and fractures at a young age which results in pain and… read more here.
Keywords: bone; bone fragility; rett syndrome; incidence fracture ... See more keywords
Even without changing the bone mineral density, alcohol consumption decreases the percentage of collagen, the thickness of bone trabeculae, and increases bone fragility.
Sign Up to like & getrecommendations! Published in 2022 at "Anais da Academia Brasileira de Ciencias"
DOI: 10.1590/0001-3765202220210661
Abstract: Excessive alcohol consumption is considered a risk factor for bone health, as it causes a reduction in mass and increases the risk of fracture. However, the determination of bone mineral density (BMD) has not always… read more here.
Keywords: alcohol; bone; bone fragility; alcohol consumption ... See more keywords
Bone health in childhood and adolescence: an overview on dual-energy X-ray absorptiometry scanning, fracture surveillance and bisphosphonate therapy for low-middle-income countries
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2023.1082413
Abstract: Bone accrual in childhood determines bone health in later life. Loss of bone strength in early life can lead to increased morbidity and reduced quality of life in childhood and adolescence. Increased availability of assessment… read more here.
Keywords: fracture; bone; dxa; childhood ... See more keywords