The circadian rhythm of calcium and bone homeostasis in Maasai
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Human Biology"
DOI: 10.1002/ajhb.23756
Abstract: Ethnic groups differ in prevalence of calcium‐related diseases. Differences in the physiology and the endogenous circadian rhythm (CR) of calcium and bone homeostasis may play a role. Thus, we aimed to investigate details of CR… read more here.
Keywords: calcium bone; circadian rhythm; calcium; bone homeostasis ... See more keywords
USP53 Regulates Bone Homeostasis by Controlling Rankl Expression in Osteoblasts and Bone Marrow Adipocytes
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.4778
Abstract: In the skeleton, osteoblasts and osteoclasts synchronize their activities to maintain bone homeostasis and integrity. Investigating the molecular mechanisms governing bone remodeling is critical and helps understand the underlying biology of bone disorders. Initially, we… read more here.
Keywords: bone marrow; bone; expression; mice ... See more keywords
Maintenance of Bone Homeostasis by DLL1‐Mediated Notch Signaling
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.25647
Abstract: Adult bone mass is maintained through a balance of the activities of osteoblasts and osteoclasts. Although Notch signaling has been shown to maintain bone homeostasis by controlling the commitment, differentiation, and function of cells in… read more here.
Keywords: bone homeostasis; dll1; bone; physiology ... See more keywords
Galectin-3 as a novel regulator of osteoblast-osteoclast interaction and bone homeostasis.
Sign Up to like & getrecommendations! Published in 2017 at "Bone"
DOI: 10.1016/j.bone.2017.08.013
Abstract: Bone tissue undergoes permanent and lifelong remodeling with a concerted action of bone-building osteoblasts and bone-resorbing osteoclasts. A precise cooperation between those two cell types is critical in the complex process of bone renewal. Galectin-3… read more here.
Keywords: bone homeostasis; galectin; bone; osteoblast osteoclast ... See more keywords
The role of gut microbiota in bone homeostasis.
Sign Up to like & getrecommendations! Published in 2020 at "Bone"
DOI: 10.1016/j.bone.2020.115317
Abstract: The gut microbiota (GM) is referred to as the second gene pool of the human body and a commensal, symbiotic, and pathogenic microorganism living in our intestines. The knowledge of the complex interaction between intestinal… read more here.
Keywords: bone homeostasis; gut; bone; gut microbiota ... See more keywords
High FGF21 levels are associated with altered bone homeostasis in HIV-1-infected patients.
Sign Up to like & getrecommendations! Published in 2017 at "Metabolism: clinical and experimental"
DOI: 10.1016/j.metabol.2017.03.014
Abstract: BACKGROUND Fibroblast growth factor-21 (FGF21) has emerged as an important regulator of glucose, lipid, and body weight homeostasis. However, recent experimental studies have reported that increased FGF21 levels may lead to bone loss. OBJECTIVE To… read more here.
Keywords: bone homeostasis; infected patients; hiv infected;
Erythromyeloid progenitors give rise to a population of osteoclasts contributing to bone homeostasis and repair
Sign Up to like & getrecommendations! Published in 2020 at "Nature cell biology"
DOI: 10.1038/s41556-019-0437-8
Abstract: Osteoclasts are multinucleated cells of the monocyte/macrophage lineage that degrade bone. Here, we used lineage tracing studies—labelling cells expressing Cx3cr1 , Csf1r or Flt3 —to identify the precursors of osteoclasts in mice. We identified an… read more here.
Keywords: bone homeostasis; erythromyeloid progenitors; bone; homeostasis repair ... See more keywords
PIP5k1β controls bone homeostasis through modulating both osteoclast and osteoblast differentiation
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Cell Biology"
DOI: 10.1093/jmcb/mjz028
Abstract: Abstract PIP5k1β is crucial to the generation of phosphotidylinosotol (4, 5)P2. PIP5k1β participates in numerous cellular activities, such as B cell and platelet activation, cell phagocytosis and endocytosis, cell apoptosis, and cytoskeletal organization. In the… read more here.
Keywords: osteoclast osteoblast; bone homeostasis; pip5k1; differentiation ... See more keywords
Erk5 in Bone Marrow Mesenchymal Stem Cells Regulates Bone Homeostasis by Preventing Osteogenesis in Adulthood.
Sign Up to like & getrecommendations! Published in 2022 at "Stem cells"
DOI: 10.1093/stmcls/sxac011
Abstract: Extracellular signal-regulated kinase 5 (Erk5) belongs to the mitogen-activated protein kinase (MAPK) family. Previously, we demonstrated that Erk5 directly phosphorylates Smad-specific E3 ubiquitin protein ligase 2 (Smurf2) at Thr249 (Smurf2Thr249) to activate its E3 ubiquitin… read more here.
Keywords: bone marrow; bone; stem cells; bone homeostasis ... See more keywords
C-reactive protein perturbs alveolar bone homeostasis: an experimental study of periodontitis and diabetes in the rat.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of clinical periodontology"
DOI: 10.1111/jcpe.13667
Abstract: AIMS To explore the role of C-reactive protein (CRP) in periodontitis and diabetes and its mechanism in alveolar bone homeostasis. MATERIALS AND METHODS In vivo, normal and Crp knockout rats were randomly divided into: control,… read more here.
Keywords: bone homeostasis; alveolar bone; periodontitis diabetes;
Progranulin is essential for bone homeostasis and immunology
Sign Up to like & getrecommendations! Published in 2022 at "Annals of the New York Academy of Sciences"
DOI: 10.1111/nyas.14905
Abstract: Intercellular communication or crosstalk between immune and skeletal cells is considered a crucial element in bone homeostasis modulation. Progranulin (PGRN) is an autocrine growth factor that is structured as beads‐on‐a‐string and participates in multiple pathophysiological… read more here.
Keywords: progranulin essential; bone; pgrn; bone homeostasis ... See more keywords