Development and challenges in setting up an international bone infection registry
Sign Up to like & getrecommendations! Published in 2019 at "Archives of Orthopaedic and Trauma Surgery"
DOI: 10.1007/s00402-019-03303-7
Abstract: Introduction Osteomyelitis is an increasing burden on the society especially due to the emergence of multiple drug-resistant organisms. The lack of a central registry that prospectively collects data on patient risk factors, laboratory test results,… read more here.
Keywords: large number; bone infection; study; registry ... See more keywords
Mesoporous silica SBA-16/hydroxyapatite-based composite for ciprofloxacin delivery to bacterial bone infection
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Sol-Gel Science and Technology"
DOI: 10.1007/s10971-017-4557-y
Abstract: The development of systems that can prevent infections and also ensure bone integration as well as regeneration have been of great interest for pharmaceutical technology. In this study, we show the synthesis of surface-functionalized mesoporous… read more here.
Keywords: sba; silica; bone infection; bone ... See more keywords
Multifunctional pH sensitive 3D scaffolds for treatment and prevention of bone infection.
Sign Up to like & getrecommendations! Published in 2018 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2017.11.009
Abstract: Multifunctional-therapeutic three-dimensional (3D) scaffolds have been prepared. These biomaterials are able to destroy the S. aureus bacterial biofilm and to allow bone regeneration at the same time. The present study is focused on the design… read more here.
Keywords: treatment prevention; scaffolds treatment; infection; bone infection ... See more keywords
A human bone infection organ model for biomaterial research.
Sign Up to like & getrecommendations! Published in 2022 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2022.03.020
Abstract: The aim of this work was to establish an organ model for staphylococcal infection of human bone samples and to investigate the influence and efficacy of a microporous β-tricalcium phosphate ceramic (β-TCP, RMS Foundation) loaded… read more here.
Keywords: bone; human bone; infection; bone infection ... See more keywords
Bone infection site targeting nanoparticle-antibiotics delivery vehicle to enhance treatment efficacy of orthopedic implant related infection
Sign Up to like & getrecommendations! Published in 2022 at "Bioactive Materials"
DOI: 10.1016/j.bioactmat.2022.02.003
Abstract: Orthopedic implants account for 99% of orthopedic surgeries, however, orthopedic implant-related infection is one of the most serious complications owing to the potential for limb-threatening sequelae and mortality. Current antibiotic treatments still lack the capacity… read more here.
Keywords: bone infection; infection; implant related; related infection ... See more keywords
Experimental study of the application of a new bone cement loaded with broad spectrum antibiotics for the treatment of bone infection.
Sign Up to like & getrecommendations! Published in 2019 at "Revista espanola de cirugia ortopedica y traumatologia"
DOI: 10.1016/j.recot.2018.10.002
Abstract: OBJECTIVES To evaluate the in vivo behaviour of a new bone cement loaded with antibiotics, in a rabbit bone infection model. MATERIAL AND METHODS Sixteen New Zealand rabbits divided into 4 groups were used, depending… read more here.
Keywords: bone cement; bone infection; new bone; bone ... See more keywords
Electroactive Mg2+-Hydroxyapatite Nanostructured Networks against Drug-Resistant Bone Infection Strains.
Sign Up to like & getrecommendations! Published in 2018 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.8b06055
Abstract: Surface colonization competition between bacteria and host cells is one of the critical factors involved in tissue/implant integration. Current biomaterials are evaluated for their ability both of withstanding favorable responses of host tissue cells and… read more here.
Keywords: infection; bone infection; electroactive mg2; hydroxyapatite nanostructured ... See more keywords
Research progress of stimulus-responsive antibacterial materials for bone infection
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.1069932
Abstract: Infection is one of the most serious complications harmful to human health, which brings a huge burden to human health. Bone infection is one of the most common and serious complications of fracture and orthopaedic… read more here.
Keywords: bone infection; infection; research progress; antibacterial materials ... See more keywords
Mini Review Therapeutic Strategies Targeting for Biofilm and Bone Infections
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.936285
Abstract: Bone infection results in a complex inflammatory response and bone destruction. A broad spectrum of bacterial species has been involved for jaw osteomyelitis, hematogenous osteomyelitis, vertebral osteomyelitis or diabetes mellitus, such as Staphylococcus aureus (S.… read more here.
Keywords: biofilm bone; therapeutic strategies; bone infection; bone ... See more keywords
Mesoporous Silica Nanoparticles for the Treatment of Complex Bone Diseases: Bone Cancer, Bone Infection and Osteoporosis
Sign Up to like & getrecommendations! Published in 2020 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics12010083
Abstract: Bone diseases, such as bone cancer, bone infection and osteoporosis, constitute a major issue for modern societies as a consequence of their progressive ageing. Even though these pathologies can be currently treated in the clinic,… read more here.
Keywords: diseases bone; bone cancer; bone infection; bone ... See more keywords
Cu-Doped Hollow Bioactive Glass Nanoparticles for Bone Infection Treatment
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14040845
Abstract: In search of new approaches to treat bone infection and prevent drug resistance development, a nanosystem based on hollow bioactive glass nanoparticles (HBGN) of composition 79.5SiO2-(18-x)CaO-2.5P2O5-xCuO (x = 0, 2.5 or 5 mol-% CuO) was… read more here.
Keywords: glass nanoparticles; bone infection; hollow bioactive; bioactive glass ... See more keywords