Bone and Joint‐on‐Chip Platforms: Construction Strategies and Applications
Sign Up to like & getrecommendations! Published in 2024 at "Small Methods"
DOI: 10.1002/smtd.202400436
Abstract: Organ‐on‐a‐chip, also known as “tissue chip,” is an advanced platform based on microfluidic systems for constructing miniature organ models in vitro. They can replicate the complex physiological and pathological responses of human organs. In recent… read more here.
Keywords: joint chip; chip platforms; construction; chip ... See more keywords
Impact of paediatric antimicrobial stewardship program in haematogenous bone and joint infections
Sign Up to like & getrecommendations! Published in 2025 at "European Journal of Pediatrics"
DOI: 10.1007/s00431-025-06258-7
Abstract: Antimicrobial stewardship programs (ASP) reduce the inappropriate use of antimicrobial agents. Traditionally, paediatric osteoarticular infections have been treated with prolonged intravenous antibiotics; however, evidence suggests that shorter intravenous therapy followed by oral narrow-spectrum antibiotics is… read more here.
Keywords: hospital; antimicrobial stewardship; haematogenous bone; joint infections ... See more keywords
The occurrence of bone and joint cancers and their association with rural living and radon exposure in Iowa
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Geochemistry and Health"
DOI: 10.1007/s10653-022-01261-5
Abstract: Primary bone and joint cancers are rare and understudied, yet these neoplasms are difficult to treat and impact all age groups. To explore the long-term changes in the occurrence of bone and joint cancers, patients… read more here.
Keywords: joint cancers; radon; bone joint; occurrence bone ... See more keywords
Bisphosphonates, Bone and Joint Pain
Sign Up to like & getrecommendations! Published in 2021 at "Current Osteoporosis Reports"
DOI: 10.1007/s11914-021-00687-7
Abstract: Bisphosphonates (BPs) have an established role in a number of diseases including osteoporosis, but the role of BPs for treating symptomatic conditions other than bone metastases is less clear. We review recent data on the… read more here.
Keywords: joint pain; osteoporosis; bone joint; bps ... See more keywords
The role of sphingosine 1-phosphate metabolism in bone and joint pathologies and ectopic calcification.
Sign Up to like & getrecommendations! Published in 2019 at "Bone"
DOI: 10.1016/j.bone.2019.115087
Abstract: Sphingolipids display important functions in various pathologies such as cancer, obesity, diabetes, cardiovascular or neurodegenerative diseases. Sphingosine, sphingosine 1-phosphate (S1P), and ceramide are the central molecules of sphingolipid metabolism. Sphingosine kinases 1 and 2 (SK1… read more here.
Keywords: metabolism; calcification; bone joint; sphingosine ... See more keywords
Activity of telavancin against Gram-positive pathogens isolated from bone and joint infections in North American, Latin American, European and Asia-Pacific nations.
Sign Up to like & getrecommendations! Published in 2017 at "Diagnostic microbiology and infectious disease"
DOI: 10.1016/j.diagmicrobio.2017.03.003
Abstract: Telavancin was tested against a worldwide collection of Gram-positive pathogens (967) isolated from bone and joint infections (BJI). Most BJI isolates were from the United States (US) (49.9%) followed by Europe (26.4%), Latin America (LATAM;… read more here.
Keywords: gram positive; telavancin; isolated bone; joint infections ... See more keywords
Protective effects of polydatin against bone and joint disorders: the in vitro and in vivo evidence so far.
Sign Up to like & getrecommendations! Published in 2023 at "Nutrition research reviews"
DOI: 10.1017/s0954422423000082
Abstract: Polydatin is an active polyphenol displaying multifaceted benefits. Recently, growing studies have noticed its potential therapeutic effects on bone and joint disorders (BJDs). Therefore, this article reviews recent in vivo and in vitro progress on… read more here.
Keywords: protective effects; joint disorders; effects polydatin; bone joint ... See more keywords
Association of the TNF-α-308, TNF-α-238 gene polymorphisms with risk of bone-joint and spinal tuberculosis: a meta-analysis
Sign Up to like & getrecommendations! Published in 2019 at "Bioscience Reports"
DOI: 10.1042/bsr20182217
Abstract: The aim of the present study was to investigate the association of TNF-α-308 and TNF-α-238 gene polymorphisms with the risk of bone-joint and spinal tuberculosis (TB) by meta-analysis. By searching PubMed, Web of Science, Wanfang… read more here.
Keywords: spinal tuberculosis; joint spinal; gene polymorphisms; bone joint ... See more keywords
P-65. Results from A Phase 2 Clinical Trial for Treatment of Bone And Joint Infections with Afabicin, A First-in-Class Selective Anti-Staphylococcal Antibiotic
Sign Up to like & getrecommendations! Published in 2025 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofae631.272
Abstract: Abstract Background Staphylococci are the most common causative pathogens in bone and joint infections (BJI). Treatment for BJI is a major clinical challenge, with recurrent and persistent infections occurring in 40% of patients. Afabicin is… read more here.
Keywords: treatment; debiopharm international; joint infections; international salary ... See more keywords
P-77. Ceftaroline versus Daptomycin as Definitive Treatment for Methicillin-Resistant Staphylococcus aureus Bone and Joint Infections
Sign Up to like & getrecommendations! Published in 2025 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofae631.284
Abstract: Abstract Background There are no comparative effectiveness studies of ceftaroline versus other antibiotics for MRSA bone and joint infections (BJI). We retrospectively compared the clinical outcomes of patients with MRSA BJI initially treated with vancomycin… read more here.
Keywords: ceftaroline versus; definitive treatment; treatment; bone joint ... See more keywords
Enhancing the Care of Patients With Bone and Joint Infections Through Educational Interventions
Sign Up to like & getrecommendations! Published in 2025 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofaf552
Abstract: Abstract Musculoskeletal infections represent a significant proportion of the clinical workload for infectious diseases (ID) providers, often presenting complex diagnostic and therapeutic challenges. Many providers may feel inadequately prepared to manage these conditions, which require… read more here.
Keywords: educational interventions; enhancing care; patients bone; joint infections ... See more keywords