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Published in 2023 at "Biotechnology and bioengineering"
DOI: 10.1002/bit.28418
Abstract: The transition in the field of bone tissue engineering from bone regeneration to in vitro models has come with the challenge of recreating a dense and anisotropic bone-like extracellular matrix (ECM). Although the mechanism by…
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Keywords:
tissue growth;
growth organization;
bone;
bone like ... See more keywords
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Published in 2021 at "Structural and Multidisciplinary Optimization"
DOI: 10.1007/s00158-021-02870-x
Abstract: Graded porous structures combine robustness of porous structures and high stiffness of bulk designs. This study aims to design optimized graded porous bone-like structures through a novel multi-material topology optimization approach, which generalizes the concept…
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Keywords:
multi material;
topology;
porosity;
material ... See more keywords
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Published in 2022 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2022.121451
Abstract: Currently, most in vitro engineered bone tissues do not contain viable blood vessel systems, so the vascularization depends on post-implantation angiogenesis from the host, which is often insufficient for repairing large bone defects. In this…
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Keywords:
like constructs;
bone;
bone like;
hbmscs ... See more keywords
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Published in 2017 at "Composites Science and Technology"
DOI: 10.1016/j.compscitech.2017.08.026
Abstract: Abstract Inspired by the hierarchically ordered structure of natural bones with the integration of outstanding strength and toughness, we made an endeavor to engineer ultra high molecular weight polyethylene (UHMWPE)/hydroxyapatite (HA) biocomposites with bone-like structure.…
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Keywords:
like structure;
hydroxyapatite;
structured uhmwpe;
structure ... See more keywords
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Published in 2018 at "Journal of the mechanical behavior of biomedical materials"
DOI: 10.1016/j.jmbbm.2017.09.014
Abstract: In this study, a simple, cost-effective approach of polymeric foam replication was used to produce three-dimensionally macroporous titanium scaffolds with controllable porosities and mechanical properties. Two kinds of porous titanium scaffolds with different porosities (74.7%…
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Keywords:
macroporous titanium;
titanium scaffolds;
titania;
titanium ... See more keywords
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Published in 2021 at "Journal of Physics and Chemistry of Solids"
DOI: 10.1016/j.jpcs.2021.110122
Abstract: Abstract Calcium phosphate-based bioactive materials have attracted considerable attention in recent years to repair bone defects. In particular, poorly crystalline apatites (PCA) are successfully used for bone repair and regeneration, enhancing the osteointegration and osteoconduction…
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Keywords:
apatite formation;
formation;
pca;
stage ... See more keywords
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Published in 2019 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.9b02502
Abstract: Large bone defects represent a significant challenge for clinicians and surgeons. Tissue engineering for bone regeneration represents an innovative solution for this dilemma and may yield attractive alternate bone substitutes. Three-dimensional (3D) printing with inexpensive…
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Keywords:
three dimensional;
acid scaffolds;
printed polylactic;
polylactic acid ... See more keywords
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Published in 2017 at "Nature"
DOI: 10.1038/543290a
Abstract: resistant to cracking — a property that could be exploited to produce safer cars, aeroplanes and power plants. Conventional sheet metals are prone to failure when exposed to repeated stress, because cracks, once formed, easily…
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Keywords:
materials bone;
like steel;
steel stops;
stops cracks ... See more keywords
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Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-75552-1
Abstract: Bones of humans and animals combine two unique features, namely: they are brittle yet have a very high fracture toughness linked to the tortuosity of the crack path and they have the ability to repeatedly…
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Keywords:
recovery;
temperature;
toughness recovery;
full strength ... See more keywords
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Published in 2022 at "Journal of biomaterials applications"
DOI: 10.1177/08853282221087107
Abstract: Bone-like apatite coating fabricated by biomineralization process is a facile way for surface modification of porous scaffolds to improve interfacial behaviors and thus facilitate cell attachment, proliferation, and differentiation for bone tissue engineering. In this…
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Keywords:
surface;
like apatite;
doped apatite;
apatite coating ... See more keywords
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Published in 2023 at "Bioengineering"
DOI: 10.3390/bioengineering10050567
Abstract: Material extrusion (MEX), commonly referred to as fused deposition modeling (FDM) or fused filament fabrication (FFF), is a versatile and cost-effective technique to fabricate suitable scaffolds for tissue engineering. Driven by a computer-aided design input,…
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Keywords:
scaffolds tissue;
tissue engineering;
bone;
bone like ... See more keywords