Articles with "bone metastases" as a keyword



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Development and Validation of a Nomogram for Assessing Survival in Patients With Metastatic Lung Cancer Referred for Radiotherapy for Bone Metastases

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Published in 2018 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2018.3242

Abstract: Key Points Question What are the optimal factors to use for constructing a nomogram to assess the probability of survival in patients with bone metastases arising from lung cancer? Findings This prognostic study of 477… read more here.

Keywords: bone metastases; patients metastatic; survival patients; lung cancer ... See more keywords
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Gene expression profiles define molecular subtypes of prostate cancer bone metastases with different outcomes and morphology traceable back to the primary tumor

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Published in 2019 at "Molecular Oncology"

DOI: 10.1002/1878-0261.12526

Abstract: Bone metastasis is the lethal end‐stage of prostate cancer (PC), but the biology of bone metastases is poorly understood. The overall aim of this study was therefore to explore molecular variability in PC bone metastases… read more here.

Keywords: bone metastases; expression profiles; bone; biology ... See more keywords
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Prognostic factors and survival prediction in HER2-positive breast cancer with bone metastases: A retrospective cohort study.

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Published in 2021 at "Cancer medicine"

DOI: 10.1002/cam4.4326

Abstract: BACKGROUND Bone is the most common metastatic site of breast cancer. The developmental pattern of bone metastasis differs in different molecular subtypes. The prognostic factors of HER2-positive breast cancer with bone metastases require further investigation.… read more here.

Keywords: bone metastases; her2 positive; prognostic factors; breast cancer ... See more keywords
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Bone Microenvironment‐Suppressed T Cells Increase Osteoclast Formation and Osteolytic Bone Metastases in Mice

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Published in 2022 at "Journal of Bone and Mineral Research"

DOI: 10.1002/jbmr.4615

Abstract: Immunotherapies use components of the immune system, such as T cells, to fight cancer cells, and are changing cancer treatment, causing durable responses in some patients. Bone metastases are a debilitating complication in advanced breast… read more here.

Keywords: cell; osteoclast formation; bone; bone metastases ... See more keywords
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Treatment dynamics of bone‐targeting agents among men with bone metastases from prostate cancer in the United States

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Published in 2018 at "Pharmacoepidemiology and Drug Safety"

DOI: 10.1002/pds.4360

Abstract: To examine the dynamics of treatment with 2 bone‐targeting agents (BTAs)—denosumab and zoledronic acid—among men with bone metastases from prostate cancer. read more here.

Keywords: bone targeting; bone metastases; metastases prostate; targeting agents ... See more keywords
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Key Factors in Breast Cancer Dissemination and Establishment at the Bone: Past, Present and Future Perspectives.

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Published in 2017 at "Advances in experimental medicine and biology"

DOI: 10.1007/978-981-10-6020-5_9

Abstract: Bone metastases associated with breast cancer remain a clinical challenge due to their associated morbidity, limited therapeutic intervention and lack of prognostic markers. With a continually evolving understanding of bone biology and its dynamic microenvironment,… read more here.

Keywords: bone; bone metastases; biology; breast cancer ... See more keywords
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[Differentiated treatment strategies for bone metastases of the extremities].

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Published in 2019 at "Der Orthopade"

DOI: 10.1007/s00132-019-03791-w

Abstract: BACKGROUND Bone metastases are the most common malignant bone tumours and most commonly occur in the spine, pelvis, proximal femur and proximal humerus. Prostate and breast cancer most often metastasize to the bone. DIAGNOSTICS In… read more here.

Keywords: strategies bone; bone metastases; differentiated treatment; treatment strategies ... See more keywords
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Bone metastases with multiple fluid-fluid levels from gastric cancer: a case report and review of literature

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Published in 2019 at "Skeletal Radiology"

DOI: 10.1007/s00256-018-3075-5

Abstract: We report the case of a 54-year-old man with 6 months of progressive sacral pain. Computed tomography showed a large osteolytic mass in the sacrum with multiple osteolytic foci in the ilium and lumbar spine. Magnetic… read more here.

Keywords: multiple fluid; bone metastases; fluid levels; fluid ... See more keywords
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68Ga-PSMA PET/CT in the evaluation of bone metastases in prostate cancer

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Published in 2018 at "European Journal of Nuclear Medicine and Molecular Imaging"

DOI: 10.1007/s00259-018-3936-0

Abstract: PurposeThe aims of this retrospective analysis were to compare 68Ga-PSMA PET findings and low-dose CT findings (120 kV, 30 mA), and to obtain semiquantitative and quantitative 68Ga-PSMA PET data in patients with prostate cancer (PC) bone metastases.MethodsIn… read more here.

Keywords: psma pet; bone metastases; 68ga psma;
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EANM guidelines for radionuclide therapy of bone metastases with beta-emitting radionuclides

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Published in 2018 at "European Journal of Nuclear Medicine and Molecular Imaging"

DOI: 10.1007/s00259-018-3947-x

Abstract: The skeleton is the most common metastatic site in patients with advanced cancer. Pain is a major healthcare problem in patients with bone metastases. Bone-seeking radionuclides that selectively accumulate in the bone are used to… read more here.

Keywords: medicine; bone metastases; eanm guidelines; beta emitting ... See more keywords
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Combination of denosumab and immune checkpoint inhibition: experience in 29 patients with metastatic melanoma and bone metastases

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Published in 2019 at "Cancer Immunology, Immunotherapy"

DOI: 10.1007/s00262-019-02353-5

Abstract: BackgroundPD-1 inhibition (PD-1i) is the standard of care in melanoma and other malignancies. In patients with bone metastases of solid tumors, the monoclonal antibody denosumab directed against RANKL is approved for the prevention of skeletal-related… read more here.

Keywords: melanoma; combination; bone metastases; denosumab ... See more keywords