Transcriptional downregulation of miR‐127‐3p by CTCF promotes prostate cancer bone metastasis by targeting PSMB5
Sign Up to like & getrecommendations! Published in 2019 at "FEBS Letters"
DOI: 10.1002/1873-3468.13624
Abstract: Prostate cancer (PCa) is one of the most common cancers in males and particularly tends to metastasize to bone. Currently, metastatic bone disease is incurable, and new therapies need to be developed. Our study aims… read more here.
Keywords: ctcf; bone; pca; bone metastasis ... See more keywords
MTA1 drives malignant progression and bone metastasis in prostate cancer
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12360
Abstract: Prostate cancer often metastasizes to the bone, leading to morbidity and mortality. While metastasis‐associated protein 1 (MTA1) is highly overexpressed in metastatic tumors and bone metastatic lesions, its exact role in the development of metastasis… read more here.
Keywords: metastasis; bone; bone metastasis; prostate cancer ... See more keywords
Perfusion applied to a 3D model of bone metastasis results in uniformly dispersed mechanical stimuli
Sign Up to like & getrecommendations! Published in 2018 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.26524
Abstract: Breast cancer most frequently metastasizes to the skeleton. Bone metastatic cancer is incurable and induces wide‐spread bone osteolysis, resulting in significant patient morbidity and mortality. Mechanical cues in the skeleton are an important microenvironmental parameter… read more here.
Keywords: model bone; perfusion; bone; model ... See more keywords
Differentially expressed and survival‐related proteins of lung adenocarcinoma with bone metastasis
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DOI: 10.1002/cam4.1363
Abstract: Despite recent advances in targeted and immune‐based therapies, the poor prognosis of lung adenocarcinoma (LUAD) with bone metastasis (BM) remains a challenge. First, two‐dimensional gel electrophoresis (2‐DE) was used to identify proteins that were differentially… read more here.
Keywords: lung adenocarcinoma; differentially expressed; bone metastasis; survival ... See more keywords
H19 Promotes HCC Bone Metastasis Through Reducing OPG Expression in a PPP1CA/p38MAPK-Dependent Manner and Sponging miR-200b-3p.
Sign Up to like & getrecommendations! Published in 2020 at "Hepatology"
DOI: 10.1002/hep.31673
Abstract: Bone is the second most frequent site of metastasis for hepatocellular carcinoma (HCC), which leads to an extremely poor prognosis. HCC bone metastasis is typically osteolytic, involving the activation of osteoclasts. Long non-coding RNA H19… read more here.
Keywords: metastasis; bone; bone metastasis; hcc bone ... See more keywords
Circulating Osteocalcin‐Positive Cells as a Novel Diagnostic Biomarker for Bone Metastasis in Breast Cancer Patients
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.4041
Abstract: Current diagnosis of bone metastasis (BM) in breast cancer relies on structural changes of bone that occur only in the advanced stage. A sensitive biomarker for detecting early progression of bone metastasis is urgently required.… read more here.
Keywords: bone; bone metastasis; breast cancer;
A Murine Bone Metastasis Model Using Caudal Artery Injection and Bioluminescence Imaging.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1258-3_4
Abstract: The current standard murine model of bone metastasis by using intracardiac injection (IC) has some limitations despite the great utility of this model. This fact emphasizes the need for a new murine model to accelerate… read more here.
Keywords: caudal artery; model; bone metastasis; injection ... See more keywords
Animal Models of Breast Cancer Bone Metastasis.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8997-3_17
Abstract: This chapter is designed to provide a comprehensive overview outlining the different in vivo models available for research into breast cancer bone metastasis. The main focus is to guide the researcher through the methodological processes… read more here.
Keywords: cancer bone; bone metastasis; breast cancer;
Antigen receptor therapy in bone metastasis via optimal control for different human life stages.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of mathematical biology"
DOI: 10.1007/s00285-021-01673-4
Abstract: In this work we propose a bone metastasis model using power law growth functions in order to describe the biochemical interactions between bone cells and cancer cells. Experimental studies indicate that bone remodeling cycles are… read more here.
Keywords: metastasis; different human; human life; bone metastasis ... See more keywords
Improved oncologic outcomes by ablative radiotherapy in patients with bone metastasis from hepatocellular carcinoma
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DOI: 10.1007/s00432-021-03553-2
Abstract: For bone metastasis from hepatocellular carcinoma (HCC), radiotherapy (RT) has been used a palliative treatment with little impact on survival. Currently, ablative RT is popularly used, and a more than palliative effect is expected. Herein,… read more here.
Keywords: hepatocellular carcinoma; patients bone; metastasis hepatocellular; metastasis ... See more keywords
Antiresorptive agent-related osteonecrosis of the jaw in prostate cancer patients with bone metastasis treated with bone-modifying agents
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Bone and Mineral Metabolism"
DOI: 10.1007/s00774-020-01151-9
Abstract: Introduction The incidence rate and risk factors of antiresorptive agent-related osteonecrosis of the jaw (ARONJ) in prostate cancer patients with bone metastasis are not clear. Materials and Methods We retrospectively reviewed patients’ records of prostate… read more here.
Keywords: patients bone; prostate cancer; rate; bone metastasis ... See more keywords