Kielin/chordin-like protein enhances induction of osteoblast differentiation by Bone Morphogenetic Protein-2.
Sign Up to like & getrecommendations! Published in 2023 at "FEBS open bio"
DOI: 10.1002/2211-5463.13652
Abstract: Bone morphogenetic proteins (BMPs) play a key role in embryonic differentiation for osteoblast and bone formation. Kielin/chordin-like protein (Kcp) is known to enhance the effects of BMP signaling. Here, we present ALP activity, gene expression,… read more here.
Keywords: bone; kielin chordin; bone morphogenetic; differentiation ... See more keywords
Inhibition of Bone Morphogenetic Protein Signaling Prevents Tau Pathology in iPSC Derived Neurons and PS19 Mice
Sign Up to like & getrecommendations! Published in 2024 at "Annals of Neurology"
DOI: 10.1002/ana.27149
Abstract: Many neurodegenerative disorders share a common pathologic feature involving the deposition of abnormal tau protein in the brain (tauopathies). This suggests that there may be some shared pathophysiologic mechanism(s). The largest risk factor for the… read more here.
Keywords: bone morphogenetic; pathology; protein; inhibition bone ... See more keywords
Absorbable collagen sponges loaded with recombinant bone morphogenetic protein 9 induces greater osteoblast differentiation when compared to bone morphogenetic protein 2
Sign Up to like & getrecommendations! Published in 2017 at "Clinical and Experimental Dental Research"
DOI: 10.1002/cre2.55
Abstract: The use of growth factors for the regeneration of soft and hard tissues has been utilized extensively in dental medicine over the past decade. Recently our group found that recombinant human bone morphogenetic protein 9… read more here.
Keywords: osteoblast differentiation; rhbmp9; bone morphogenetic; morphogenetic protein ... See more keywords
Bone morphogenetic protein‐2 incorporated calcium phosphate graft promotes peri‐implant bone defect healing in dogs: A pilot study
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Experimental Dental Research"
DOI: 10.1002/cre2.613
Abstract: The evaluation of three different drug delivery modes of bone morphogenetic protein‐2 (BMP‐2) in healing peri‐implant bone defects in beagle dogs. BMP‐2 was incorporated in or onto calcium phosphate (CaP) granules in various ways: (i)… read more here.
Keywords: bone; calcium phosphate; peri implant; bone morphogenetic ... See more keywords
Lack of evidence that fibrillin1 regulates bone morphogenetic protein 4 activity in kidney or lung
Sign Up to like & getrecommendations! Published in 2023 at "Developmental Dynamics"
DOI: 10.1002/dvdy.578
Abstract: The Bone morphogenetic protein 4 (BMP4) precursor protein is cleaved at two sites to generate an active ligand and inactive prodomain. The ligand and prodomain form a noncovalent complex following the first cleavage, but dissociate… read more here.
Keywords: evidence fibrillin1; lack evidence; activity; bone morphogenetic ... See more keywords
Characterization of new bone morphogenetic protein (Bmp)‐2 regulatory alleles
Sign Up to like & getrecommendations! Published in 2017 at "genesis"
DOI: 10.1002/dvg.23035
Abstract: Bone morphogenetic protein 2 (BMP2, HGNC:1069, GeneID: 650) is a classical morphogen; a molecule that acts at a distance and whose concentration influences cell proliferation, differentiation, and apoptosis. Key events requiring precise Bmp2 regulation include… read more here.
Keywords: bmp2; bone morphogenetic; morphogenetic protein; characterization new ... See more keywords
Augmentation of bone morphogenetic protein signaling in cranial neural crest cells in mice deforms skull base due to premature fusion of intersphenoidal synchondrosis
Sign Up to like & getrecommendations! Published in 2023 at "genesis"
DOI: 10.1002/dvg.23509
Abstract: Craniofacial anomalies (CFAs) are a diverse group of disorders affecting the shapes of the face and the head. Malformation of the cranial base in humans leads CFAs, such as midfacial hypoplasia and craniosynostosis. These patients… read more here.
Keywords: premature fusion; fusion; morphogenetic protein; bone morphogenetic ... See more keywords
Functional Testing of Bone Morphogenetic Protein (BMP) Pathway Variants Identified on Whole‐Exome Sequencing in a Patient with Delayed‐Onset Fibrodysplasia Ossificans Progressiva (FOP) Using ACVR1R206H ‐Specific Human Cellular and Zebrafish Models
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.4711
Abstract: Bone morphogenetic protein (BMP) signaling is critical in skeletal development. Overactivation can trigger heterotopic ossification (HO) as in fibrodysplasia ossificans progressiva (FOP), a rare, progressive disease of massive HO formation. A small subset of FOP… read more here.
Keywords: protein bmp; bmp signaling; bone; bone morphogenetic ... See more keywords
Bone morphogenetic protein 13 in hepatic stellate cells and hepatic fibrosis.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of cellular biochemistry"
DOI: 10.1002/jcb.30248
Abstract: Hepatic fibrosis can be considered as a deregulated wound healing process in response to chronic liver injury. Bone morphogenetic protein 13 (BMP13) has been described to promote bone and tendon repair. In this study, we… read more here.
Keywords: bmp13; expression; bone morphogenetic; fibrosis ... See more keywords
Association of plasma bone morphogenetic protein‐4 levels with arterial stiffness in hypertensive patients
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DOI: 10.1002/jcla.24746
Abstract: Arterial stiffness interacts with hypertension, becoming an early marker of hypertension‐mediated target organ damage. This study aimed to assess the association between plasma concentrations of bone morphogenetic protein‐4 (BMP‐4) and arterial stiffness during hypertension. read more here.
Keywords: morphogenetic protein; arterial stiffness; association plasma; bone morphogenetic ... See more keywords
Contributions of bone morphogenetic proteins in cardiac repair cells in three‐dimensional in vitro models and angiogenesis
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.2460
Abstract: One of the main efforts in myocardial tissue engineering is towards designing cardiac tissues able to rescue the reduction in heart function once implanted at the site of myocardial infarction. To date, the efficiency of… read more here.
Keywords: morphogenetic proteins; cardiac tissues; bone morphogenetic; proteins cardiac ... See more keywords