Noggin proteins are multifunctional extracellular regulators of cell signaling
Sign Up to like & getrecommendations! Published in 2022 at "Genetics"
DOI: 10.1093/genetics/iyac049
Abstract: Abstract Noggin is an extracellular cysteine knot protein that plays a crucial role in vertebrate dorsoventral patterning. Noggin binds and inhibits the activity of bone morphogenetic proteins via a conserved N-terminal clip domain. Noncanonical orthologs… read more here.
Keywords: noggin; receptor tyrosine; bone morphogenic; tyrosine kinase ... See more keywords
Bone Morphogenic Protein-2 Use for the Surgical Treatment of Acute Scaphoid Fractures and Scaphoid Nonunions
Sign Up to like & getrecommendations! Published in 2022 at "Plastic and Reconstructive Surgery"
DOI: 10.1097/prs.0000000000009416
Abstract: Background: Bone morphogenic protein-2 has demonstrated promise as an adjunct to surgically treating fractures. Its reported use in the upper extremity is limited. This study reports union rates, outcomes, and complications of scaphoid fractures treated… read more here.
Keywords: morphogenic protein; union; scaphoid fractures; bone morphogenic ... See more keywords
Reduced bone morphogenic protein signaling along the gut–neuron axis by heat shock factor promotes longevity
Sign Up to like & getrecommendations! Published in 2022 at "Aging Cell"
DOI: 10.1111/acel.13693
Abstract: Aging is a complex and highly regulated process of interwoven signaling mechanisms. As an ancient transcriptional regulator of thermal adaptation and protein homeostasis, the Heat Shock Factor, HSF‐1, has evolved functions within the nervous system… read more here.
Keywords: morphogenic protein; signaling along; heat shock; shock factor ... See more keywords
A facile one-stage treatment of critical bone defects using a calcium sulfate/hydroxyapatite biomaterial providing spatiotemporal delivery of bone morphogenic protein–2 and zoledronic acid
Sign Up to like & getrecommendations! Published in 2020 at "Science Advances"
DOI: 10.1126/sciadv.abc1779
Abstract: Combining BMP-2 and zoledronic acid is a recipe for creating “synthetic autologous bone” to treat large bone defects. Bone morphogenic proteins (BMPs) are the only true osteoinductive molecules. Despite being tremendously potent, their clinical use… read more here.
Keywords: delivery; bone; bone morphogenic; zoledronic acid ... See more keywords
Insights into the Role of Gremlin-1, a Bone Morphogenic Protein Antagonist, in Cancer Initiation and Progression
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10020301
Abstract: The bone morphogenic protein (BMP) antagonist Gremlin-1 is a biologically significant regulator known for its crucial role in tissue differentiation and embryonic development. Nevertheless, it has been reported that Gremlin-1 can exhibit its function through… read more here.
Keywords: morphogenic protein; gremlin; role; initiation progression ... See more keywords
Structure and Expression Characteristics of Bone Morphogenic Protein 3 in Fracture of Human Jaw Bones
Sign Up to like & getrecommendations! Published in 2018 at "Research Journal of Pharmacy and Technology"
DOI: 10.5958/0974-360x.2018.00229.9
Abstract: Bone morphogenetic proteins (BMPs) are a group of growth factors, which are also known as cytokines and as metabologens. Bone morphogenetic proteins (BMPs) are multi-functional growth factors belonging to the transforming growth factor s (TGF-s)… read more here.
Keywords: morphogenic protein; bone morphogenic; structure expression; fracture ... See more keywords