Functional Biomaterials for Bone Regeneration: A Lesson in Complex Biology
Sign Up to like & getrecommendations! Published in 2020 at "Advanced Functional Materials"
DOI: 10.1002/adfm.201909874
Abstract: Bone is a hard yet dynamic tissue with remarkable healing capacities. Research to date has greatly advanced the understanding of how bone heals and has led to marked success in the treatment of bone injuries.… read more here.
Keywords: bone; bone regeneration; biomaterials bone; functional biomaterials ... See more keywords
Microfluidic 3D Printing Responsive Scaffolds with Biomimetic Enrichment Channels for Bone Regeneration
Sign Up to like & getrecommendations! Published in 2021 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202105190
Abstract: Tissue‐engineered scaffolds have been extensively explored for treating bone defects; however, slow and insufficient vascularization throughout the scaffolds remains a key challenge for further application. Herein, a versatile microfluidic 3D printing strategy to fabricate black… read more here.
Keywords: printing responsive; responsive scaffolds; bone regeneration; scaffolds biomimetic ... See more keywords
Mechanics‐Resilient HA/SIS‐Based Composite Scaffolds with ROS‐Scavenging and Bacteria‐Resistant Capacity to Address Infected Bone Regeneration
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202315382
Abstract: To address and regenerate infected bone defects complicated by issues such as inflammation and bone resorption, and to promote bone regeneration, this study focuses on the development of a composite scaffold with reactive oxygen species… read more here.
Keywords: composite scaffold; mechanics; infected bone; bone regeneration ... See more keywords
Hierarchical Mineralized Collagen Coated Zn Membrane to Tailor Cell Microenvironment for Guided Bone Regeneration
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202412695
Abstract: Maxillofacial bone defects caused by trauma, infections, tumors, and congenital disorders have become a significant global health concern. An ideal guided bone regeneration (GBR) membrane is expected to not only act as a barrier but… read more here.
Keywords: hierarchical mineralized; bone regeneration; bone; guided bone ... See more keywords
Mechanical Stimulus and Metabolic Responses by Cryo‐Printing Anisotropic Scaffolds for Achieving Promoted Bone Regeneration
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202416546
Abstract: 3D scaffolds are essential as they serve as extracellular matrix (ECM)‐like platforms to provide cells with mechanical support and facilitate their attachment for bone regeneration. As an emerging personalized treatment technology, 3D printing has been… read more here.
Keywords: anisotropic; mechanical stimulus; anisotropic scaffolds; bone regeneration ... See more keywords
Injectable Bismuth‐Based Composite Enable Bone Defect Repair for Osteosarcoma Treatment and Mild Magnetothermal Bone Regeneration
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202501317
Abstract: Bone implant materials are essential for treating bone defects in clinical, however, current options face challenges in minimally invasive implantation, precise in situ molding, and long surgical times with large incisions. To address these drawbacks,… read more here.
Keywords: bismuth based; bismuth; repair; bone regeneration ... See more keywords
Ion‐in‐Conjugation‐Enabled Remineralized Scaffold for Spatiotemporal Control of Infection and Bone Regeneration
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202517239
Abstract: Infectious bone defects remain a major clinical challenge requiring simultaneous infection control and bone regeneration. Here, a dual‐functional scaffold integrating antimicrobial and osteogenic activities is developed via sequential ion delivery. An acellular demineralized bone matrix… read more here.
Keywords: control; bone regeneration; infection; bone ... See more keywords
Crab Cuticle‐Derived Bilayer Membrane Orchestrates Spatiotemporal Maintenance and Osteogenic Activity for Guided Bone Regeneration
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202523211
Abstract: Guided bone regeneration (GBR) has emerged as the most prevalent therapeutic approach for alveolar bone augmentation. However, current GBR membranes struggle to balance mechanical strength, space‐maintaining capacity, osteogenic activity, and biodegradability. Nature offers elegant solutions… read more here.
Keywords: osteogenic activity; crab cuticle; bone regeneration; bone ... See more keywords
3D‐Plotted Beta‐Tricalcium Phosphate Scaffolds with Smaller Pore Sizes Improve In Vivo Bone Regeneration and Biomechanical Properties in a Critical‐Sized Calvarial Defect Rat Model
Sign Up to like & getrecommendations! Published in 2018 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.201800441
Abstract: Due to the difficulty in fabricating bioceramic scaffolds with smaller pore sizes by the current 3D printing technique, the effect of smaller pore sizes (below 400 µm) of 3D printed bioceramic scaffolds on the bone… read more here.
Keywords: scaffolds smaller; bone regeneration; pore sizes; smaller pore ... See more keywords
Molecular Mass-Dependent Resorption and Bone Regeneration of 3D Printed PPF Scaffolds in a Critical-Sized Rat Cranial Defect Model.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced healthcare materials"
DOI: 10.1002/adhm.201900646
Abstract: The emergence of additive manufacturing has afforded the ability to fabricate intricate, high resolution, and patient-specific polymeric implants. However, the availability of biocompatible resins with tunable resorption profiles remains a significant hurdle to clinical translation.… read more here.
Keywords: bone; resorption; molecular mass; bone regeneration ... See more keywords
Self-Folding 3D Silk Biomaterial Rolls to Facilitate Axon and Bone Regeneration.
Sign Up to like & getrecommendations! Published in 2020 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202000530
Abstract: Biomaterial scaffold designs are needed for self-organizing features related to tissue formation while also simplifying the fabrication processes involved. Toward this goal, silk protein-based self-folding scaffolds to support 3D cell culture, while providing directional guidance… read more here.
Keywords: bone regeneration; silk; self folding; folding silk ... See more keywords