Bone regenerative potential of the selective sphingosine 1-phosphate receptor modulator siponimod: In vitro characterisation using osteoblast and endothelial cells.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2020.173262
Abstract: The repair of critical bone defects remains a significant therapeutic challenge. While the implantation of drug-eluting scaffolds is an option, a drug with the optimal pharmacological properties has not yet been identified. Agents acting at… read more here.
Keywords: sphingosine phosphate; bone regenerative; endothelial cells; modulator siponimod ... See more keywords
Oxygen-Generating Biomaterials for Translational Bone Regenerative Engineering.
Sign Up to like & getrecommendations! Published in 2023 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c20715
Abstract: Successful regeneration of critical-size defects remains one of the significant challenges in regenerative engineering. These large-scale bone defects are difficult to regenerate and are often reconstructed with matrices that do not provide adequate oxygen levels… read more here.
Keywords: regenerative engineering; bone; bone regenerative; oxygen ... See more keywords
Physio-Chemical and Biological Characterization of Novel HPC (Hydroxypropylcellulose):HAP (Hydroxyapatite):PLA (Poly Lactic Acid) Electrospun Nanofibers as Implantable Material for Bone Regenerative Application
Sign Up to like & getrecommendations! Published in 2022 at "Polymers"
DOI: 10.3390/polym15010155
Abstract: The research on extracellular matrix (ECM) is new and developing area that covers cell proliferation and differentiation and ensures improved cell viability for different biomedical applications. Extracellular matrix not only maintains biological functions but also… read more here.
Keywords: pla; bone regenerative; material; poly lactic ... See more keywords