Bone-targeted exosomes: Strategies and applications.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202203361
Abstract: As the global population ages, bone-related diseases have increasingly become a major social problem threatening human health. Exosomes, as natural cell products, have been used to treat bone-related diseases due to their superior biocompatibility, biological… read more here.
Keywords: bone related; bone; bone targeted; related diseases ... See more keywords
SNPs in bone-related miRNAs are associated with the osteoporotic phenotype
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-00641-7
Abstract: Biogenesis and function of microRNAs can be influenced by genetic variants in the pri-miRNA sequences leading to phenotypic variability. This study aims to identify single nucleotide polymorphisms (SNPs) affecting the expression levels of bone-related mature… read more here.
Keywords: bone related; osteoporotic phenotype; mir 3679; bmd ... See more keywords
Clinical characteristics and prognosis of multiple myeloma with bone-related extramedullary disease at diagnosis
Sign Up to like & getrecommendations! Published in 2018 at "Bioscience Reports"
DOI: 10.1042/bsr20171697
Abstract: Multiple myeloma (MM) is a hematological neoplasm which results in diffuse or focal bone infiltration and extramedullary lesions. It’s reported that infiltration of organs by plasma cells indicated worse prognosis, but the prognosis of patients… read more here.
Keywords: bone related; prognosis; multiple myeloma; related extramedullary ... See more keywords
Hydroxyapatite for bone related applications derived from sea shell waste by simpleprecipitation method
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Asian Ceramic Societies"
DOI: 10.1080/21870764.2020.1749373
Abstract: ABSTRACT The nano-hydroxyapatite (NHAp), NHAp/PEG and NHAp/PVP have been derived from Clam shell by precipitation method. The presence of characteristic FTIR peaks and XRD planes indicates the formation of NHAp. Surface morphology of NHAp, NHAp/PEG… read more here.
Keywords: bone related; method; pvp; shell ... See more keywords
Effects of Aleurone Layer Extract From Black Rice (Oryza sativa L.) on Bone Mineral Density and Bone-Related Biomarkers of Ovariectomized Rats (FS14-05-19).
Sign Up to like & getrecommendations! Published in 2019 at "Current developments in nutrition"
DOI: 10.1093/cdn/nzz038.fs14-05-19
Abstract: Objectives Black rice contains functional compounds, including anthocyanins. In a previous study, black rice increased bone mineral density and strength in ovariectomized rats, although its biological effects on bone-related markers have not been evaluated. The… read more here.
Keywords: ovariectomized rats; bone related; bone; black rice ... See more keywords
Yunnan Baiyao diminishes lipopolysaccharide-induced inflammation in osteoclasts.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of food biochemistry"
DOI: 10.1111/jfbc.13182
Abstract: Yunnan Baiyao (YNBY) has been refined for hundreds of years and has become a treasure of proprietary Chinese medicine that has significant curative effects in the field of hemostasis, blood circulation, and callus. In past… read more here.
Keywords: anti inflammatory; bone related; yunnan baiyao; mapk wnt5a ... See more keywords
Therapeutic application of hydrogels for bone-related diseases
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.998988
Abstract: Bone-related diseases caused by trauma, infection, and aging affect people’s health and quality of life. The prevalence of bone-related diseases has been increasing yearly in recent years. Mild bone diseases can still be treated with… read more here.
Keywords: hydrogels bone; application hydrogels; related diseases; bone related ... See more keywords
Stat3 Signaling Pathway: A Future Therapeutic Target for Bone-Related Diseases
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.897539
Abstract: Signal transducer and activator of transcription 3 (Stat3) is activated by phosphorylation and translocated to the nucleus to participate in the transcriptional regulation of DNA. Increasing evidences point that aberrant activation or deletion of the… read more here.
Keywords: stat3 signaling; related diseases; bone related; target bone ... See more keywords
Therapeutic Potential of Triptolide in Treating Bone-Related Disorders
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.905576
Abstract: Triptolide, a diterpene triepoxide, is a pharmacologically active compound isolated from a Chinese medicinal herb Tripterygium wilfordii Hook F (TwHF). Triptolide has attracted considerable attention in recent times due to its multiple biological and pharmaceutical… read more here.
Keywords: treating bone; related disorders; triptolide treating; bone related ... See more keywords
Roles of Gut Microbiome in Bone Homeostasis and Its Relationship with Bone-Related Diseases
Sign Up to like & getrecommendations! Published in 2022 at "Biology"
DOI: 10.3390/biology11101402
Abstract: Simple Summary In recent years, there has been increasing evidence that communication between the skeletal system and the gut microbiome (GM) can influence bone health and that the GM is a key regulator of bone… read more here.
Keywords: bone related; bone; related diseases; gut microbiome ... See more keywords
Identification of Key Genes and Pathways Associated with PIEZO1 in Bone-Related Disease Based on Bioinformatics
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23095250
Abstract: PIEZO1 is a mechano-sensitive ion channel that can sense various forms of mechanical stimuli and convert them into biological signals, affecting bone-related diseases. The present study aimed to identify key genes and signaling pathways in… read more here.
Keywords: bone related; key genes; bone; analysis ... See more keywords