Bone Strength Estimated by Micro‐Finite Element Analysis (µFEA) Is Heritable and Shares Genetic Predisposition With Areal BMD: The Framingham Study
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DOI: 10.1002/jbmr.3200
Abstract: Genetic factors contribute to the risk of bone fractures, partly because of effects on bone strength. High‐resolution peripheral quantitative computed tomography (HR‐pQCT) estimates bone strength using micro‐finite element analysis (µFEA). The goal of this study… read more here.
Keywords: failure load; bone; bone strength; analysis ... See more keywords
Bone Microarchitecture and Strength in Long‐Standing Type 1 Diabetes
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DOI: 10.1002/jbmr.4517
Abstract: Type 1 diabetes (T1DM) is associated with an increased fracture risk, specifically at nonvertebral sites. The influence of glycemic control and microvascular disease on skeletal health in long‐standing T1DM remains largely unknown. We aimed to… read more here.
Keywords: strength; bone strength; bone; long standing ... See more keywords
Zinc supplementation improves antioxidant status, and organic zinc is more efficient than inorganic zinc in improving the bone strength of aged laying hens
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DOI: 10.1002/vms3.896
Abstract: Abstract Background There have been some reports indicating that supplementation of zinc could alleviate the negative effects of age on egg quality in laying hens. However, information regarding these positive effects on health and zinc… read more here.
Keywords: bone strength; zinc; zinc supplementation; laying hens ... See more keywords
Weight loss in men in late life and bone strength and microarchitecture: a prospective study
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DOI: 10.1007/s00198-018-4489-6
Abstract: SummaryWeight loss in men in late life was associated with lower bone strength. In contrast, weight gain was not associated with a commensurate increase in bone strength. Future studies should measure concurrent changes in weight… read more here.
Keywords: bone strength; weight loss; loss men; loss ... See more keywords
Age-related reference data of bone microarchitecture, volumetric bone density, and bone strength parameters in a population of healthy Brazilian men: an HR-pQCT study
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DOI: 10.1007/s00198-021-06288-5
Abstract: In a cross-sectional cohort of 340 healthy Brazilian men aged 20 to 92 years, data on density, structure, and strength of the distal radius and tibia were obtained using high-resolution peripheral quantitative computed tomography (HR-pQCT)… read more here.
Keywords: age; bone; reference; density ... See more keywords
Cortical bone mineral density is increased by the cathepsin K inhibitor ONO-5334, which leads to a robust increase in bone strength: results from a 16-month study in ovariectomised cynomolgus monkeys
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Bone and Mineral Metabolism"
DOI: 10.1007/s00774-018-0968-2
Abstract: This study evaluated the long-term effects of the cathepsin K inhibitor ONO-5334 on bone mass and strength in ovariectomised (OVX) cynomolgus monkeys. Animals were assigned to one of the following six groups: Sham (non-OVX), OVX… read more here.
Keywords: bone mineral; ono 5334; cortical bone; bone ... See more keywords
Assisted Physical Exercise for Improving Bone Strength in Preterm Infants Less than 35 Weeks Gestation: A Randomized Controlled Trial
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DOI: 10.1007/s13312-018-1242-3
Abstract: ObjectiveTo compare the efficacy of daily assisted physical exercise (starting from one week of postnatal age) on bone strength at 40 weeks of post menstrual age to no intervention in infants born between 27 and… read more here.
Keywords: age; exercise; bone; assisted physical ... See more keywords
Phantomless calibration of CT scans for measurement of BMD and bone strength-Inter-operator reanalysis precision.
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DOI: 10.1016/j.bone.2017.07.029
Abstract: Patient-specific phantomless calibration of computed tomography (CT) scans has the potential to simplify and expand the use of pre-existing clinical CT for quantitative bone densitometry and bone strength analysis for diagnostic and monitoring purposes. In… read more here.
Keywords: phantomless calibration; bone strength; calibration; phantomless ... See more keywords
The microbial metagenome and bone tissue composition in mice with microbiome-induced reductions in bone strength.
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DOI: 10.1016/j.bone.2019.06.010
Abstract: The genetic components of microbial species that inhabit the body are known collectively as the microbiome. Modifications to the microbiome have been implicated in disease processes throughout the body and have recently been shown to… read more here.
Keywords: microbiome; bone; mice; bone strength ... See more keywords
Disuse-induced loss of bone mineral density and bone strength is attenuated by post-lactational bone gain in NMRI mice.
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DOI: 10.1016/j.bone.2019.115183
Abstract: Lactation in mice is associated with a substantial bone loss, which almost completely recovers within four weeks after weaning. The post-lactational recovery mechanism is considered one of the most potent physiological bone anabolic responses in… read more here.
Keywords: bone; mice; bone strength; lactation ... See more keywords
Anti-interleukin-6 receptor antibody prevents loss of bone structure and bone strength in collagen-induced arthritis mice
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DOI: 10.1080/03009742.2017.1416667
Abstract: Objective: Rheumatoid arthritis (RA) is a disease that typically induces secondary osteoporosis, which increases the risk of bone fractures. Anti-interleukin-6 (IL-6) receptor antibody is used to treat RA; however, its effect on bone strength is… read more here.
Keywords: receptor antibody; bone; bone strength; bone structure ... See more keywords