Real-time PCR assays that detect genes for botulinum neurotoxin A–G subtypes
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DOI: 10.3389/fmicb.2024.1382056
Abstract: The role of Real-Time PCR assays for surveillance and rapid screening for pathogens is garnering more and more attention because of its versatility and ease of adoption. The goal of this study was to design,… read more here.
Keywords: bont bont; pcr assays; bont; real time ... See more keywords
A Comprehensive Structural Analysis of Clostridium botulinum Neurotoxin A Cell-Binding Domain from Different Subtypes
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DOI: 10.3390/toxins15020092
Abstract: Botulinum neurotoxins (BoNTs) cause flaccid neuromuscular paralysis by cleaving one of the SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) complex proteins. BoNTs display high affinity and specificity for neuromuscular junctions, making them one of the… read more here.
Keywords: structural analysis; cell binding; bont bont; bont ... See more keywords
Characterization of Serotype CD Mosaic Botulinum Neurotoxin in Comparison with Serotype C and A
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DOI: 10.3390/toxins15020123
Abstract: Botulinum neurotoxin (BoNT), produced by Clostridium botulinum, cleaves proteins involved in neurotransmitter release, thereby triggering flaccid paralyses, which are responsible for botulism. BoNT is classified into seven serotypes (BoNT/A-G); BoNT/A and BoNT/B are used as… read more here.
Keywords: bont bont; bont; mosaic; botulinum neurotoxin ... See more keywords