Heterologous prime-boost immunization with vesiculovirus-based vectors expressing HBV Core antigen induces CD8+ T cell responses in naïve and persistently infected mice and protects from challenge.
Sign Up to like & getrecommendations! Published in 2019 at "Antiviral research"
DOI: 10.1016/j.antiviral.2019.05.014
Abstract: Chronic hepatitis B virus (HBV) infections cause more than 800,000 deaths per year and currently approved treatments do not cure the disease. Because a hallmark of acute infection resolution is the presence of functional CD8+… read more here.
Keywords: prime boost; hbv; boost immunization; core ... See more keywords
Editorial: Deciphering immunological mechanisms of spatial and temporal vaccine delivery
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2024.1354796
Abstract: of the in fl uenza vaccine may improve the quality of the induced immune responses over that induced by prime-boost immunization. They immunized the mice with 5 µg of whole inactivated in fl uenza vaccine… read more here.
Keywords: delivery; boost immunization; deciphering immunological; editorial deciphering ... See more keywords
A Prime-Boost Immunization Strategy with Vaccinia Virus Expressing Novel gp120 Envelope Glycoprotein from a CRF02_AG Isolate Elicits Cross-Clade Tier 2 HIV-1 Neutralizing Antibodies
Sign Up to like & getrecommendations! Published in 2020 at "Vaccines"
DOI: 10.3390/vaccines8020171
Abstract: Development of new immunogens eliciting broadly neutralizing antibodies (bNAbs) is a main priority for the HIV-1 vaccine field. Envelope glycoproteins from non-B-non-C HIV-1clades have not been fully explored as components of a vaccine. We produced… read more here.
Keywords: boost immunization; prime boost; hiv; envelope ... See more keywords