Antigenicity of Leishmania-Activated C-Kinase Antigen (LACK) in Human Peripheral Blood Mononuclear Cells, and Protective Effect of Prime-Boost Vaccination With pCI-neo-LACK Plus Attenuated LACK-Expressing Vaccinia Viruses in Hamsters
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DOI: 10.3389/fimmu.2018.00843
Abstract: Leishmania-activated C-kinase antigen (LACK) is a highly conserved protein among Leishmania species and is considered a viable vaccine candidate for human leishmaniasis. In animal models, prime-boost vaccination with LACK-expressing plasmids plus attenuated vaccinia viruses (modified… read more here.
Keywords: prime boost; boost vaccination; vaccinia; antigen ... See more keywords
Prime-Boost Vaccination With Covaxin/BBV152 Induces Heightened Systemic Cytokine and Chemokine Responses
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DOI: 10.3389/fimmu.2021.752397
Abstract: Covaxin/BBV152 is a whole virion inactivated SARS-CoV-2 vaccine. The effect of prime-boost vaccination with Covaxin on systemic immune responses is not known. We investigated the effect of Covaxin on the plasma levels of a wide… read more here.
Keywords: prime boost; boost vaccination; covaxin bbv152; vaccination ... See more keywords
BNT162b2 booster after heterologous prime-boost vaccination induces potent neutralizing antibodies and T cell reactivity against SARS-CoV-2 Omicron BA.1 in young adults
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DOI: 10.3389/fimmu.2022.882918
Abstract: In light of the decreasing immune protection against symptomatic SARS-CoV-2 infection after initial vaccinations and the now dominant immune-evasive Omicron variants, ‘booster’ vaccinations are regularly performed to restore immune responses. Many individuals have received a… read more here.
Keywords: vaccination; prime boost; sars cov; young adults ... See more keywords
Efficacy of COVID-19 Booster Vaccines in Patients with Hematologic Malignancies: Experiences in a Real-World Scenario
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DOI: 10.3390/cancers14225512
Abstract: Simple Summary The current study provides data on the efficacy of COVID-19 prime-boost vaccines in 200 patients with hematologic and predominantly lymphoid malignancies as well as a risk-adapted guidance for the management of weak and… read more here.
Keywords: vaccination; prime boost; booster; covid breakthrough ... See more keywords
Efficacy of Heterologous Prime-Boost Vaccination with H3N2 Influenza Viruses in Pre-Immune Individuals: Studies in the Pig Model
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DOI: 10.3390/v12090968
Abstract: In a previous study in influenza-naïve pigs, heterologous prime-boost vaccination with monovalent, adjuvanted whole inactivated vaccines (WIV) based on the European swine influenza A virus (SwIAV) strain, A/swine/Gent/172/2008 (G08), followed by the US SwIAV strain,… read more here.
Keywords: h3n2; prime boost; heterologous prime; influenza ... See more keywords
Durability of Antibody Response after Primary Pneumococcal Double-Dose Prime-Boost Vaccination in Adult Kidney Transplant Recipients and Candidates: 18-Month Follow-Up in a Non-Blinded, Randomised Clinical Trial
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DOI: 10.3390/vaccines10071091
Abstract: Background: Pneumococcal prime-boost vaccination is recommended for solid organ transplant recipients and candidates. The long-term durability of the antibody (AB) response is unknown. The same applies to a dose-dependent immune response. Methods: We studied the… read more here.
Keywords: prime boost; kidney transplant; transplant recipients; response ... See more keywords
Homologous and Heterologous Prime-Boost Vaccination: Impact on Clinical Severity of SARS-CoV-2 Omicron Infection among Hospitalized COVID-19 Patients in Belgium
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DOI: 10.3390/vaccines11020378
Abstract: We investigated effectiveness of (1) mRNA booster vaccination versus primary vaccination only and (2) heterologous (viral vector–mRNA) versus homologous (mRNA–mRNA) prime-boost vaccination against severe outcomes of BA.1, BA.2, BA.4 or BA.5 Omicron infection (confirmed by… read more here.
Keywords: vaccination; prime boost; covid; omicron infection ... See more keywords
Heterologous Prime-Boost Vaccination with Commercial FMD Vaccines Elicits a Broader Immune Response than Homologous Prime-Boost Vaccination in Pigs
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DOI: 10.3390/vaccines11030551
Abstract: Three commercial vaccines are administered in domestic livestock farms for routine vaccination to aid for foot-and-mouth disease (FMD) control in Korea. Each vaccine contains distinct combinations of inactivated serotype O and A FMD virus (FMDV)… read more here.
Keywords: vaccination; prime boost; fmd; immune response ... See more keywords