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Propofol Protects Rat Hypoglossal Motoneurons in an In Vitro Model of Excitotoxicity by Boosting GABAergic Inhibition and Reducing Oxidative Stress

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Published in 2017 at "Neuroscience"

DOI: 10.1016/j.neuroscience.2017.10.019

Abstract: In brainstem motor networks, hypoglossal motoneurons (HMs) play the physiological role of driving tongue contraction, an activity critical for inspiration, phonation, chewing and swallowing. HMs are an early target of neurodegenerative diseases like amyotrophic lateral… read more here.

Keywords: propofol; boosting gabaergic; excitotoxicity; inhibition ... See more keywords