A comparative study of the complete lipopolysaccharide structures and biosynthesis loci of Bordetella avium, B. hinzii, and B. trematum.
Sign Up to like & getrecommendations! Published in 2019 at "Biochimie"
DOI: 10.1016/j.biochi.2018.12.011
Abstract: A dozen species of human and animal pathogens have been described to date in the Bordetella genus, with the majority being respiratory tract pathogens. Bordetella avium lipopolysaccharides have been shown to be important virulence factors… read more here.
Keywords: bordetella; bordetella avium; avium hinzii; study ... See more keywords
Bordetella bronchiseptica in non-cystic fibrosis bronchiectasis
Sign Up to like & getrecommendations! Published in 2018 at "Respiratory Medicine Case Reports"
DOI: 10.1016/j.rmcr.2018.08.023
Abstract: Bordetella bronchiseptica is a rare pulmonary infection, often associated with zoonotic transmission. It has been described in immunocompromised patients and those with underlying pulmonary disease. However, there are no case series describing the spectrum of… read more here.
Keywords: non cystic; cystic fibrosis; bordetella; fibrosis bronchiectasis ... See more keywords
Primary transcriptome analysis reveals importance of IS elements for the shaping of the transcriptional landscape of Bordetella pertussis
Sign Up to like & getrecommendations! Published in 2018 at "RNA Biology"
DOI: 10.1080/15476286.2018.1462655
Abstract: ABSTRACT Bordetella pertussis is the causative agent of whooping cough, a respiratory disease still considered as a major public health threat and for which recent re-emergence has been observed. Constant reshuffling of Bordetella pertussis genome… read more here.
Keywords: analysis reveals; transcriptome analysis; bordetella; primary transcriptome ... See more keywords
The Adjuvant Bordetella Colonization Factor A Attenuates Alum-Induced Th2 Responses and Enhances Bordetella pertussis Clearance from Mouse Lungs
Sign Up to like & getrecommendations! Published in 2018 at "Infection and Immunity"
DOI: 10.1128/iai.00935-17
Abstract: ABSTRACT The reemergence of pertussis or whooping cough in several countries highlights the need for better vaccines. Acellular pertussis vaccines (aPV) contain alum as the adjuvant and elicit Th2-biased immune responses that are less effective… read more here.
Keywords: bordetella; immune responses; bordetella pertussis; bordetella colonization ... See more keywords
The BvgS PAS Domain, an Independent Sensory Perception Module in the Bordetella bronchiseptica BvgAS Phosphorelay
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Bacteriology"
DOI: 10.1128/jb.00286-19
Abstract: Despite high rates of vaccination, pertussis, a severe, highly contagious respiratory disease caused by the bacterium Bordetella pertussis, has reemerged as a significant health threat. In Bordetella pertussis and the closely related species Bordetella bronchiseptica,… read more here.
Keywords: pas domain; activity; bvgas; domain ... See more keywords
Blockade of the Adenylate Cyclase Toxin Synergizes with Opsonizing Antibodies to Protect Mice against Bordetella pertussis
Sign Up to like & getrecommendations! Published in 2022 at "mBio"
DOI: 10.1128/mbio.01527-22
Abstract: Despite high vaccine coverage in developed countries, the incidence of pertussis has increased in recent decades, often leading to severe consequences for sensitive groups, including infants. For this reason, improving the efficacy of pertussis vaccines… read more here.
Keywords: protection; adenylate cyclase; bordetella; act ... See more keywords
Bordetella Dermonecrotic Toxin Is a Neurotropic Virulence Factor That Uses CaV3.1 as the Cell Surface Receptor
Sign Up to like & getrecommendations! Published in 2020 at "mBio"
DOI: 10.1128/mbio.03146-19
Abstract: Bordetella pertussis, which causes pertussis, a contagious respiratory disease, produces three major protein toxins, pertussis toxin, adenylate cyclase toxin, and dermonecrotic toxin (DNT), for which molecular actions have been elucidated. The former two toxins are… read more here.
Keywords: dermonecrotic toxin; infection; pertussis; dnt ... See more keywords
Bbvac: A Live Vaccine Candidate That Provides Long-Lasting Anamnestic and Th17-Mediated Immunity against the Three Classical Bordetella spp.
Sign Up to like & getrecommendations! Published in 2022 at "mSphere"
DOI: 10.1128/msphere.00892-21
Abstract: Infectious diseases are a major cause of morbidity and mortality in the United States, accounting for over 40 million hospitalizations since 1998. Therefore, novel vaccine strategies are imperative, which can be improved with a better… read more here.
Keywords: three classical; bordetella spp; bordetella; immunity ... See more keywords
BopN is a Gatekeeper of the Bordetella Type III Secretion System
Sign Up to like & getrecommendations! Published in 2023 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.04112-22
Abstract: The T3SS is utilized by many Gram-negative bacteria to deliver effector proteins from bacterial cytosol directly into infected host cell cytoplasm in a regulated and targeted manner. Pathogenic bordetellae use the T3SS to inject the… read more here.
Keywords: bordetella; btea; secretion; host ... See more keywords
Epidemiology of pertussis in Casablanca (Morocco): contribution of conventional and molecular diagnosis tools
Sign Up to like & getrecommendations! Published in 2017 at "BMC Infectious Diseases"
DOI: 10.1186/s12879-017-2452-3
Abstract: BackgroundPertussis, a vaccine preventable disease, is still responsible of significant morbidity and mortality around the world, mostly in newborns. The aim of the present study was (1) to introduce pertussis surveillance in the major pediatric… read more here.
Keywords: bordetella; dna; casablanca morocco; epidemiology ... See more keywords
Cytotoxicity of the effector protein BteA was attenuated in Bordetella pertussis by insertion of an alanine residue
Sign Up to like & getrecommendations! Published in 2020 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1008512
Abstract: Bordetella bronchiseptica and Bordetella pertussis are closely related respiratory pathogens that evolved from a common bacterial ancestor. While B. bronchiseptica has an environmental reservoir and mostly establishes chronic infections in a broad range of mammals,… read more here.
Keywords: bordetella; insertion; btea; cytotoxicity ... See more keywords