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Published in 2023 at "Biotechnology progress"
DOI: 10.1002/btpr.3335
Abstract: A mathematical model is proposed for Bordetella pertussis with the main goal to better understand and describe the relation between cell growth, oxidative stress and NADPH levels under different oxidative conditions. The model is validated…
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Keywords:
stress;
oxidative stress;
bordetella pertussis;
model ... See more keywords
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Published in 2018 at "ChemMedChem"
DOI: 10.1002/cmdc.201800332
Abstract: A series of 13 acyclic nucleoside phosphonates (ANPs) as bisamidate prodrugs was prepared. Five compounds were found to be non‐cytotoxic and selective inhibitors of Bordetella pertussis adenylate cyclase toxin (ACT) in J774A.1 macrophage cell‐based assays.…
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Keywords:
potent selective;
adenylate cyclases;
bacillus anthracis;
bordetella pertussis ... See more keywords
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Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/5584_2019_401
Abstract: The evolution of Bordetella pertussis from a common ancestor similar to Bordetella bronchiseptica has occurred through large-scale gene loss, inactivation and rearrangements, largely driven by the spread of insertion sequence element repeats throughout the genome.…
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Keywords:
evolution;
bordetella pertussis;
pertussis;
genomics changing ... See more keywords
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Published in 2018 at "Anales De Pediatria"
DOI: 10.1016/j.anpede.2017.10.007
Abstract: Abstract Objective Describe the epidemiological and clinical pattern of Bordetella pertussis infection (whooping cough) among hospitalised infants less than one year-old in a paediatric hospital in Gran Canaria. Patients and methods A retrospective review of…
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Keywords:
gran canaria;
infection;
bordetella pertussis;
pertussis infection ... See more keywords
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Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.02.113
Abstract: Proteolytic degradation of the ∼100-kDa isolated RTX (Repeat-in-ToXin) subdomain (CyaA-RTX) of the Bordetella pertussis CyaA-hemolysin (CyaA-Hly) was evidently detected upon solely-prolonged incubation. Here, a truncated CyaA-Hly fragment (CyaA-HP/BI) containing hydrophobic and acylation regions connected with…
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Keywords:
zn2 dependent;
cyaa;
cyaa rtx;
bordetella pertussis ... See more keywords
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Published in 2019 at "Biochemical Engineering Journal"
DOI: 10.1016/j.bej.2019.107359
Abstract: Abstract The response of Bordetella pertussis to induced oxidative stress during fermentation was assessed. B. pertussis is the causal agent of whooping cough in humans and purified pertactin (PRN) is used as one of the…
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Keywords:
stress;
oxidative stress;
bordetella pertussis;
protein production ... See more keywords
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Published in 2019 at "Comparative immunology, microbiology and infectious diseases"
DOI: 10.1016/j.cimid.2019.03.010
Abstract: In spite of high vaccination coverage in the Expanded Program of Immunization (EPI), pertussis has not been eradicated yet and the re-emergence of the disease is still reported worldwide. The genetic divergence study of circulating…
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Keywords:
vaccine strains;
sequence typing;
pertussis;
strains bordetella ... See more keywords
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Published in 2019 at "Infectious Disease Modelling"
DOI: 10.1016/j.idm.2019.06.001
Abstract: Bordetella pertussis (B. pertussis) is the causative agent of pertussis, also referenced as whooping cough. Although pertussis has been appropriately controlled by routine immunization of infants, it has experienced a resurgence since the beginning of…
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Keywords:
analysis;
infection;
bordetella pertussis;
pertussis infection ... See more keywords
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Published in 2020 at "Medical Hypotheses"
DOI: 10.1016/j.mehy.2020.109779
Abstract: Abstract The novel coronavirus COVID-19 follows transmission route and clinical presentation of all community-acquired coronaviruses. Instead, the rate of transmission is significative higher, with a faster spread of the virus responsible of the worldwide outbreak…
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Keywords:
bordetella pertussis;
tetanus diphtheria;
immune system;
epidemiology ... See more keywords
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Published in 2017 at "Respiratory medicine"
DOI: 10.1016/j.rmed.2017.10.009
Abstract: INTRODUCTION Hajj pilgrimage is the biggest and longest mass gathering in the Muslim world. Annually, about 50% of more than 2.5 million pilgrims participating in this ritual get involved in severe devastating coughs. Most coughs…
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Keywords:
chlamydia pneumonia;
hajj;
bordetella pertussis;
study ... See more keywords
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Published in 2017 at "Epidemiology and Infection"
DOI: 10.1017/s0950268816003332
Abstract: SUMMARY Pertussis is a worldwide acute respiratory disease caused by the bacterium Bordetella pertussis. Despite high vaccine coverage, the bacterium continues to circulate in populations and is still one of the most common vaccine-preventable diseases.…
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Keywords:
isolated central;
bordetella pertussis;
strains isolated;
pertussis strains ... See more keywords