Modeling the Effect of Oxidative Stress on Bordetella pertussis Fermentations.
Sign Up to like & getrecommendations! Published in 2023 at "Biotechnology progress"
DOI: 10.1002/btpr.3335
Abstract: A mathematical model is proposed for Bordetella pertussis with the main goal to better understand and describe the relation between cell growth, oxidative stress and NADPH levels under different oxidative conditions. The model is validated… read more here.
Keywords: stress; oxidative stress; bordetella pertussis; model ... See more keywords
Nucleobase Modified Adefovir (PMEA) Analogues as Potent and Selective Inhibitors of Adenylate Cyclases from Bordetella pertussis and Bacillus anthracis
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DOI: 10.1002/cmdc.201800332
Abstract: A series of 13 acyclic nucleoside phosphonates (ANPs) as bisamidate prodrugs was prepared. Five compounds were found to be non‐cytotoxic and selective inhibitors of Bordetella pertussis adenylate cyclase toxin (ACT) in J774A.1 macrophage cell‐based assays.… read more here.
Keywords: potent selective; adenylate cyclases; bacillus anthracis; bordetella pertussis ... See more keywords
How Genomics Is Changing What We Know About the Evolution and Genome of Bordetella pertussis.
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DOI: 10.1007/5584_2019_401
Abstract: The evolution of Bordetella pertussis from a common ancestor similar to Bordetella bronchiseptica has occurred through large-scale gene loss, inactivation and rearrangements, largely driven by the spread of insertion sequence element repeats throughout the genome.… read more here.
Keywords: evolution; bordetella pertussis; pertussis; genomics changing ... See more keywords
Clinical-epidemiological study of Bordetella pertussis infection in the Gran Canaria island in the period, 2008–2016☆☆☆
Sign Up to like & getrecommendations! Published in 2018 at "Anales De Pediatria"
DOI: 10.1016/j.anpede.2017.10.007
Abstract: Abstract Objective Describe the epidemiological and clinical pattern of Bordetella pertussis infection (whooping cough) among hospitalised infants less than one year-old in a paediatric hospital in Gran Canaria. Patients and methods A retrospective review of… read more here.
Keywords: gran canaria; infection; bordetella pertussis; pertussis infection ... See more keywords
Zn2+-dependent autocatalytic activity of the Bordetella pertussis CyaA-hemolysin.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.02.113
Abstract: Proteolytic degradation of the ∼100-kDa isolated RTX (Repeat-in-ToXin) subdomain (CyaA-RTX) of the Bordetella pertussis CyaA-hemolysin (CyaA-Hly) was evidently detected upon solely-prolonged incubation. Here, a truncated CyaA-Hly fragment (CyaA-HP/BI) containing hydrophobic and acylation regions connected with… read more here.
Keywords: zn2 dependent; cyaa; cyaa rtx; bordetella pertussis ... See more keywords
Impact of oxidative stress on protein production by Bordetella pertussis for vaccine production
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical Engineering Journal"
DOI: 10.1016/j.bej.2019.107359
Abstract: Abstract The response of Bordetella pertussis to induced oxidative stress during fermentation was assessed. B. pertussis is the causal agent of whooping cough in humans and purified pertactin (PRN) is used as one of the… read more here.
Keywords: stress; oxidative stress; bordetella pertussis; protein production ... See more keywords
Genetic analysis of clinical and vaccine strains of Bordetella pertussis by Pulsed-Field Gel Electrophoresis (PFGE), Multi Locus Sequence Typing (MLST) and serotyping.
Sign Up to like & getrecommendations! Published in 2019 at "Comparative immunology, microbiology and infectious diseases"
DOI: 10.1016/j.cimid.2019.03.010
Abstract: In spite of high vaccination coverage in the Expanded Program of Immunization (EPI), pertussis has not been eradicated yet and the re-emergence of the disease is still reported worldwide. The genetic divergence study of circulating… read more here.
Keywords: vaccine strains; sequence typing; pertussis; strains bordetella ... See more keywords
Investigation of temporal and spatial heterogeneities of the immune responses to Bordetella pertussis infection in the lung and spleen of mice via analysis and modeling of dynamic microarray gene expression data
Sign Up to like & getrecommendations! Published in 2019 at "Infectious Disease Modelling"
DOI: 10.1016/j.idm.2019.06.001
Abstract: Bordetella pertussis (B. pertussis) is the causative agent of pertussis, also referenced as whooping cough. Although pertussis has been appropriately controlled by routine immunization of infants, it has experienced a resurgence since the beginning of… read more here.
Keywords: analysis; infection; bordetella pertussis; pertussis infection ... See more keywords
SARS – CoV-2: Reasons of epidemiology of severe ill disease cases and therapeutic approach using trivalent vaccine (tetanus, diphtheria and Bordetella pertussis)
Sign Up to like & getrecommendations! Published in 2020 at "Medical Hypotheses"
DOI: 10.1016/j.mehy.2020.109779
Abstract: Abstract The novel coronavirus COVID-19 follows transmission route and clinical presentation of all community-acquired coronaviruses. Instead, the rate of transmission is significative higher, with a faster spread of the virus responsible of the worldwide outbreak… read more here.
Keywords: bordetella pertussis; tetanus diphtheria; immune system; epidemiology ... See more keywords
Serological study of Bordetella Pertussis, Mycoplasma Pneumonia and Chlamydia Pneumonia in Iranian hajj pilgrims with prolonged cough illnesses: A follow-up study.
Sign Up to like & getrecommendations! Published in 2017 at "Respiratory medicine"
DOI: 10.1016/j.rmed.2017.10.009
Abstract: INTRODUCTION Hajj pilgrimage is the biggest and longest mass gathering in the Muslim world. Annually, about 50% of more than 2.5 million pilgrims participating in this ritual get involved in severe devastating coughs. Most coughs… read more here.
Keywords: chlamydia pneumonia; hajj; bordetella pertussis; study ... See more keywords
The characterization of Bordetella pertussis strains isolated in the Central-Western region of Brazil suggests the selection of a specific genetic profile during 2012–2014 outbreaks
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DOI: 10.1017/s0950268816003332
Abstract: SUMMARY Pertussis is a worldwide acute respiratory disease caused by the bacterium Bordetella pertussis. Despite high vaccine coverage, the bacterium continues to circulate in populations and is still one of the most common vaccine-preventable diseases.… read more here.
Keywords: isolated central; bordetella pertussis; strains isolated; pertussis strains ... See more keywords