DARPP‐32 distinguishes a subset of adult‐born neurons in zebra finch HVC
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.25245
Abstract: Adult male zebra finches (Taeniopygia guttata) continually incorporate adult‐born neurons into HVC, a telencephalic brain region necessary for the production of learned song. These neurons express activity‐dependent immediate early genes (e.g., zenk and c‐fos) following… read more here.
Keywords: darpp; hvc; hvc nns; adult ... See more keywords
Spatial exploration induced expression of immediate early genes Fos and Zif268 in adult-born neurons Is reduced after pentylenetetrazole kindling
Sign Up to like & getrecommendations! Published in 2019 at "Brain Research Bulletin"
DOI: 10.1016/j.brainresbull.2019.07.003
Abstract: Seizure activity stimulates adult neurogenesis, the birth of new neurons, in the hippocampus. Many new neurons that develop in the presence of repeatedly induced seizures acquire abnormal morphological and functional characteristics that can promote network… read more here.
Keywords: adult born; fos zif268; zif268; expression ... See more keywords
Development and Refinement of Functional Properties of Adult-Born Neurons
Sign Up to like & getrecommendations! Published in 2017 at "Neuron"
DOI: 10.1016/j.neuron.2017.09.039
Abstract: New neurons appear only in a few regions of the adult mammalian brain and become integrated into existing circuits. Little is known about the functional development of individual neurons in vivo. We examined the functional life… read more here.
Keywords: development refinement; adult born; refinement functional; born neurons ... See more keywords
Functions of adult-born neurons in hippocampal memory interference and indexing
Sign Up to like & getrecommendations! Published in 2019 at "Nature Neuroscience"
DOI: 10.1038/s41593-019-0484-2
Abstract: The dentate gyrus–CA3 circuit of the hippocampus is continuously modified by the integration of adult-born dentate granule cells (abDGCs). All abDGCs undergo a prolonged period of maturation, during which they exhibit heightened synaptic plasticity and… read more here.
Keywords: adult born; support; memory interference; hippocampal memory ... See more keywords
Afferents modulate newborn neurons
Sign Up to like & getrecommendations! Published in 2019 at "Science"
DOI: 10.1126/science.364.6440.542-o
Abstract: Neuroscience What is the role of adult neurogenesis in learning, memory, and mood? Luna et al. found that adult-born neurons either inhibited or excited the dentate gyrus, depending on whether synaptic inputs originated from the… read more here.
Keywords: dentate gyrus; science; adult; afferents modulate ... See more keywords
Multifaceted circuit functions of adult-born neurons
Sign Up to like & getrecommendations! Published in 2019 at "F1000Research"
DOI: 10.12688/f1000research.20642.1
Abstract: The dentate gyrus continually produces new neurons throughout life. Behavioral studies in rodents and network models show that new neurons contribute to normal dentate functions, but there are many unanswered questions about how the relatively… read more here.
Keywords: adult born; multifaceted circuit; born neurons; circuit functions ... See more keywords
Sex Differences in the Spatial Behavior Functions of Adult-Born Neurons in Rats
Sign Up to like & getrecommendations! Published in 2022 at "eNeuro"
DOI: 10.1523/eneuro.0054-22.2022
Abstract: Abstract Adult neurogenesis modifies hippocampal circuits and behavior, but removing newborn neurons does not consistently alter spatial processing, a core function of the hippocampus. Additionally, little is known about sex differences in neurogenesis since few… read more here.
Keywords: adult born; males females; sex; neurogenesis ... See more keywords
Running throughout Middle-Age Keeps Old Adult-Born Neurons Wired
Sign Up to like & getrecommendations! Published in 2023 at "eNeuro"
DOI: 10.1523/eneuro.0084-23.2023
Abstract: Abstract Exercise may prevent or delay aging-related memory loss and neurodegeneration. In rodents, running increases the number of adult-born neurons in the dentate gyrus (DG) of the hippocampus, in association with improved synaptic plasticity and… read more here.
Keywords: adult; middle age; adult born; memory ... See more keywords
Adult-born neurons add flexibility to hippocampal memories
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2023.1128623
Abstract: Although most neurons are generated embryonically, neurogenesis is maintained at low rates in specific brain areas throughout adulthood, including the dentate gyrus of the mammalian hippocampus. Episodic-like memories encoded in the hippocampus require the dentate… read more here.
Keywords: adult born; dentate gyrus; born neurons; neurons add ... See more keywords