Full‐length genomic sequencing and characterization of Borna disease virus 1 isolates: Lessons in epidemiology
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Medical Virology"
DOI: 10.1002/jmv.25951
Abstract: Borna disease virus 1 (BoDV‐1) is a nonsegmented, negative‐strand RNA virus that infects mammals including humans. BoDV‐1 strains occur globally, dominate the species Mammalian 1 bornavirus, and display highly conserved genomes and persistent infection (brain,… read more here.
Keywords: borna disease; epidemiology; disease virus; bodv ... See more keywords
Borna disease virus docks on neuronal DNA double-strand breaks to replicate and dampens neuronal activity
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DOI: 10.1016/j.isci.2021.103621
Abstract: Summary Borna disease viruses (BoDV) have recently emerged as zoonotic neurotropic pathogens. These persistent RNA viruses assemble nuclear replication centers (vSPOT) in close interaction with the host chromatin. However, the topology of this interaction and… read more here.
Keywords: double strand; borna disease; dna double; strand breaks ... See more keywords
Linkage between the leader sequence and leader RNA production in Borna disease virus-infected cells.
Sign Up to like & getrecommendations! Published in 2017 at "Virology"
DOI: 10.1016/j.virol.2017.07.011
Abstract: The 3'-untranslated region (UTR) of the non-segmented, negative-strand (NNS) RNA viral genome is called the leader sequence, and functions as the promoter for viral replication and transcription. NNS RNA viruses also use the sequence as… read more here.
Keywords: disease virus; production; leader; borna disease ... See more keywords
Low prevalence of Borna disease virus 1 (BoDV-1) IgG antibodies in humans from areas endemic for animal Borna disease of Southern Germany
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-56839-4
Abstract: Borna disease virus-1 (BoDV-1) was recently discovered as cause of severe and often fatal encephalitis in humans. BoDV-1 is known to cause neurological disease in horses and sheep mainly in South and Central Germany. The… read more here.
Keywords: borna disease; disease virus; bodv; disease ... See more keywords
BUD23-TRMT112 interacts with the L protein of Borna disease virus and mediates the chromosomal tethering of viral ribonucleoproteins.
Sign Up to like & getrecommendations! Published in 2021 at "Microbiology and immunology"
DOI: 10.1111/1348-0421.12934
Abstract: Persistent intranuclear infection is an uncommon infection strategy among RNA viruses. However, Borna disease virus 1 (BoDV-1), a nonsegmented, negative-strand RNA virus, maintains viral infection in the cell nucleus by forming structured aggregates of viral… read more here.
Keywords: disease virus; bodv; infection; chromosomal tethering ... See more keywords
Prominent Efficacy of Amantadine against Human Borna Disease Virus Infection In Vitro and In Vivo. Comment on Fink et al. Amantadine Inhibits SARS-CoV-2 In Vitro. Viruses 2021, 13, 539
Sign Up to like & getrecommendations! Published in 2022 at "Viruses"
DOI: 10.3390/v14030494
Abstract: Amantadine (1-amino-adamantane) is a versatile antiviral compound which has been licensed for decades against influenza viruses. During the Corona pandemic, its effect to inhibit SARS-CoV-2 in vitro has been investigated. However, an in vivo oral… read more here.
Keywords: disease virus; borna disease; sars cov; cov vitro ... See more keywords
Borna Disease Virus 1 Phosphoprotein Forms a Tetramer and Interacts with Host Factors Involved in DNA Double-Strand Break Repair and mRNA Processing
Sign Up to like & getrecommendations! Published in 2022 at "Viruses"
DOI: 10.3390/v14112358
Abstract: Determining the structural organisation of viral replication complexes and unravelling the impact of infection on cellular homeostasis represent important challenges in virology. This may prove particularly useful when confronted with viruses that pose a significant… read more here.
Keywords: disease virus; repair mrna; phosphoprotein; borna disease ... See more keywords
Vaccination against Borna Disease: Overview, Vaccine Virus Characterization and Investigation of Live and Inactivated Vaccines
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DOI: 10.3390/v14122706
Abstract: (1) Background: Vaccination of horses and sheep against Borna disease (BD) was common in endemic areas of Germany in the 20th century but was abandoned in the early 1990s. The recent occurrence of fatal cases… read more here.
Keywords: vaccination; borna disease; vaccine; virus ... See more keywords
IFN-γ-Based ELISpot as a New Tool to Detect Human Infections with Borna Disease Virus 1 (BoDV-1): A Pilot Study
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DOI: 10.3390/v15010194
Abstract: More than 40 human infections with the zoonotic Borna disease virus 1 (BoDV-1) have been reported to German health authorities from endemic regions in southern and eastern Germany. Diagnosis of a confirmed case is based… read more here.
Keywords: virus bodv; human infections; borna disease; disease virus ... See more keywords
Detection of Antibodies against Borna Disease Virus Proteins in an Autistic Child and Her Mother.
Sign Up to like & getrecommendations! Published in 2017 at "Japanese journal of infectious diseases"
DOI: 10.7883/yoken.jjid.2017.e001
Abstract: Volume 70, no 2, p.225-227, 2017. Page 226, Figure 1B and C should appear as shown below. read more here.
Keywords: disease virus; detection antibodies; virus proteins; proteins autistic ... See more keywords