Exosome‐Coated 10B Carbon Dots for Precise Boron Neutron Capture Therapy in a Mouse Model of Glioma In Situ
Sign Up to like & getrecommendations! Published in 2021 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202100969
Abstract: Novel boron‐containing carbon dots (BCDs) are designed and prepared for boron neutron capture therapy (BNCT) with superior water solubility and excellent optical property for tracking 10B in vitro and in vivo. Encapsulation of BCDs using… read more here.
Keywords: boron; glioma; bcd exos; boron neutron ... See more keywords
Engineering Novel Targeted Boron-10-Enriched Theranostic Nanomedicine to Combat against Murine Brain Tumors via MR Imaging-Guided Boron Neutron Capture Therapy.
Sign Up to like & getrecommendations! Published in 2017 at "Advanced materials"
DOI: 10.1002/adma.201700850
Abstract: Glioblastoma multiforme (GBM) is a very common type of "incurable" malignant brain tumor. Although many treatment options are currently available, most of them eventually fail due to its recurrence. Boron neutron capture therapy (BNCT) emerges… read more here.
Keywords: capture therapy; boron neutron; neutron capture; boron ... See more keywords
Tumor Eradication by Boron Neutron Capture Therapy with 10 B-enriched Hexagonal Boron Nitride Nanoparticles Grafted with Poly(glycerol).
Sign Up to like & getrecommendations! Published in 2023 at "Advanced materials"
DOI: 10.1002/adma.202301479
Abstract: Boron neutron capture therapy (BNCT) has emerged as a treatment modality with high precision and efficacy of intractable tumors. At the core of effective tumor BNCT are 10 B carriers with facile preparation as well as… read more here.
Keywords: enriched hexagonal; neutron capture; boron; boron neutron ... See more keywords
Next generation of boron neutron capture therapy (BNCT) agents for cancer treatment.
Sign Up to like & getrecommendations! Published in 2023 at "Medicinal research reviews"
DOI: 10.1002/med.21964
Abstract: Boron neutron capture therapy (BNCT) is one of the most promising treatments among neutron capture therapies due to its long-term clinical application and unequivocally obtained success during clinical trials. Boron drug and neutron play an equivalent crucial… read more here.
Keywords: therapy bnct; neutron capture; boron; boron neutron ... See more keywords
Block copolymer‐boron cluster conjugate for effective boron neutron capture therapy of solid tumors
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Controlled Release"
DOI: 10.1016/j.jconrel.2017.03.036
Abstract: &NA; Boron neutron capture therapy is a promising tumor treatment method, though its wide application has been limited due to the poor tumor selectivity and intracellular delivery of 10B‐compounds. Here, block copolymer‐boron cluster conjugate based… read more here.
Keywords: capture therapy; block copolymer; boron neutron; neutron capture ... See more keywords
Sensing changes in tumor during boron neutron capture therapy using PET with a collimator: Simulation study
Sign Up to like & getrecommendations! Published in 2020 at "Nuclear Engineering and Technology"
DOI: 10.1016/j.net.2020.02.014
Abstract: Abstract The purpose of this study was to demonstrate the feasibility of sensing changes in a tumor during boron neutron capture therapy (BNCT) using a Monte Carlo simulation tool. In the simulation, an epi-thermal neutron… read more here.
Keywords: neutron; tumor boron; boron neutron; sensing changes ... See more keywords
Design of a scintillator-based prompt gamma camera for boron-neutron capture therapy: Comparison of SrI2 and GAGG using Monte-Carlo simulation
Sign Up to like & getrecommendations! Published in 2020 at "Nuclear Engineering and Technology"
DOI: 10.1016/j.net.2020.07.010
Abstract: Abstract Boron–neutron capture therapy (BNCT) is a cancer treatment method that exploits the high neutron reactivity of boron. Monitoring the prompt gamma rays (PGs) produced during neutron irradiation is essential for ensuring the accuracy and… read more here.
Keywords: neutron; boron neutron; scintillator; neutron capture ... See more keywords
Design, Synthesis, and Biological Evaluation of Boron-Containing Macrocyclic Polyamines and Their Zinc(II) Complexes for Boron Neutron Capture Therapy
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Medicinal Chemistry"
DOI: 10.1021/acs.jmedchem.1c00445
Abstract: Boron neutron capture therapy (BNCT) is a binary therapeutic method for cancer treatment based on the use of a combination of a cancer-specific drug containing boron-10 (10B) and thermal neutron irradiation. For successful BNCT, 10B-containing… read more here.
Keywords: capture therapy; boron neutron; neutron capture; cancer ... See more keywords
The Development of Boron Analysis and Imaging in Boron Neutron Capture Therapy (BNCT).
Sign Up to like & getrecommendations! Published in 2022 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.1c00810
Abstract: Boron neutron capture therapy (BNCT) is a selective biological targeted nuclide technique for cancer therapy. It has the following attractive features: good targeting, high effectiveness, and causes slight damage to surrounding healthy tissue compared with… read more here.
Keywords: therapy bnct; neutron capture; therapy; boron ... See more keywords
Sweet Battle of the Epimers─Continued Exploration of Monosaccharide-Derived Delivery Agents for Boron Neutron Capture Therapy.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.3c00119
Abstract: Boron neutron capture therapy (BNCT) is a cancer therapy in which boron delivery agents play a crucial role. In theory, delivery agents with high tumor targeting capabilities can lead to selective eradication of tumor cells… read more here.
Keywords: neutron capture; delivery agents; boron neutron; capture therapy ... See more keywords
A Potential Boron Neutron Capture Therapy Agent Selectively Suppresses High-Grade Glioma: In Vitro and in Vivo Exploration.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.3c00152
Abstract: Glioblastoma (GBM), as the most central nervous system (CNS) intractable disease, has spoiled millions of lives due to its high mortality. Even though several efforts have been made, the existing treatments have had limited success.… read more here.
Keywords: vivo; neutron capture; therapy; boron ... See more keywords