Adaptable boronate ester hydrogels with tunable viscoelastic spectra to probe timescale dependent mechanotransduction.
Sign Up to like & getrecommendations! Published in 2019 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2019.119430
Abstract: Cells are capable of sensing the differences in elastic and viscous properties (i.e., the 'viscoelasticity') of their tissue microenvironment and responding accordingly by changing their transcriptional activity and modifying their behaviors. When designing viscoelastic materials… read more here.
Keywords: viscoelastic spectra; timescale dependent; mechanotransduction; tunable viscoelastic ... See more keywords
Boronate-ester crosslinked hyaluronic acid hydrogels for dihydrocaffeic acid delivery and fibroblasts protection against UVB irradiation.
Sign Up to like & getrecommendations! Published in 2020 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2020.116845
Abstract: Herein, we exploit the dynamic nature and pH dependence of complexes between phenylboronic acid and diol-containing molecules to control the release of an anti-photoaging agent, dihydrocaffeic acid (DHCA), from a dynamic covalent hydrogel (HG). The… read more here.
Keywords: protection uvb; dihydrocaffeic acid; hyaluronic acid; acid ... See more keywords
Boron Neutron Capture Therapy Enhanced by Boronate Ester Polymer Micelles: Synthesis, Stability, and Tumor Inhibition Studies
Sign Up to like & getrecommendations! Published in 2024 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.4c00298
Abstract: Boron neutron capture therapy (BNCT) targets invasive, radioresistant cancers but requires a selective and high B-10 loading boron drug. This manuscript investigates boron-rich poly(ethylene glycol)-block-(poly(4-vinylphenyl boronate ester)) polymer micelles synthesized via atom transfer radical polymerization… read more here.
Keywords: ester polymer; boron neutron; neutron capture; tumor ... See more keywords
Boronate Ester Hydrogels for Biomedical Applications: Challenges and Opportunities
Sign Up to like & getrecommendations! Published in 2024 at "Chemistry of Materials"
DOI: 10.1021/acs.chemmater.4c00507
Abstract: Boronate ester (BE) hydrogels are increasingly used for biomedical applications. The dynamic nature of these molecular networks enables bond rearrangement, which is associated with viscoelasticity, injectability, printability, and self-healing, among other properties. BEs are also… read more here.
Keywords: chemistry; biomedical applications; ester hydrogels; culture ... See more keywords
Metal-Stabilized Boronate Ester Cages.
Sign Up to like & getrecommendations! Published in 2021 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.1c01719
Abstract: Molecular cages with arylboronate ester caps at the vertices are described. The cages were obtained by metal-templated polycondensation reactions of a tris(2-formylpyridine oxime) ligand with arylboronic acids. Suited templates are triflate or triflimide salts of… read more here.
Keywords: ester cages; metal stabilized; ester; boronate ester ... See more keywords
A Water-Stable Boronate Ester Cage
Sign Up to like & getrecommendations! Published in 2024 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.3c12002
Abstract: The reversible condensation of catechols and boronic acids to boronate esters is a paradigm reaction in dynamic covalent chemistry. However, facile backward hydrolysis is detrimental for stability and has so far prevented applications for boronate-based… read more here.
Keywords: stable boronate; water stable; boronate ester; boronate ... See more keywords
Synthesis and Chiral Self-Sorting of Spirobifluorene-Containing Boronate Ester Cages
Sign Up to like & getrecommendations! Published in 2025 at "Organic Chemistry Frontiers"
DOI: 10.1039/d4qo02012j
Abstract: 2,2’-Functionalization induces axial chirality within the orthogonal aromatic scaffold of 9,9’-bispirofluorene. By implementing boronic acids at these positions, well-suited precursors for chiral boronate ester cages are generated. As a key... read more here.
Keywords: synthesis chiral; chiral self; boronate ester; ester cages ... See more keywords