Enantioselective α-C(sp3)-H Borylation of Masked Primary Alcohols Enabled by Iridium Catalysis.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.4c14890
Abstract: Functional group-directed site- and enantioselective C(sp3)-H functionalization of alcohols or masked alcohols represents a formidable challenge. We herein report the first example of iridium-catalyzed asymmetric α-C(sp3)-H borylation of primary alcohol-derived carbamates by the judicious choice… read more here.
Keywords: masked primary; enantioselective sp3; borylation masked; sp3 borylation ... See more keywords