Enantioselective synthesis of cyclic α-aminoboronates via copper-catalyzed dearomative borylation of 4-quinolinols.
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DOI: 10.1039/d2cc00027j
Abstract: A highly enantioselective and regioselective dearomative borylation of 4-quinolinols was developed using a Cu(I)/(R,R)-Ph-BPE catalyst for efficient synthesis of unprecedented heterocyclic α-amino boronates, a new class of compounds potentially relevant to drug discovery, in generally… read more here.
Keywords: borylation quinolinols; enantioselective synthesis; dearomative borylation; synthesis cyclic ... See more keywords