Copper-catalyzed borylative cyclization of 1,n-enynyl phosphates leading to five- to eight-membered cyclic 1,4-dienyl boronates
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DOI: 10.1016/j.tetlet.2017.02.059
Abstract: Abstract We report here a room temperature, efficient, and broadly applicable copper-catalyzed borylative cyclization of 1,n-enynyl (n = 6–9) phosphates for the concise synthesis of structurally diverse 5–8 membered cyclic 1,4-dienyl boronates, which represents the first Cu-catalyzed… read more here.
Keywords: cyclization enynyl; enynyl phosphates; copper catalyzed; membered cyclic ... See more keywords
Borylative Cyclization of 1,6-Allenynes Driven by BCl3.
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DOI: 10.1021/acs.orglett.1c03062
Abstract: A metal-free intramolecular borylative cyclization of 1,6-allenynes driven by BCl3 was developed. This method provides a general and practical strategy to construct valuable pyrrolidines containing all-carbon quaternary centers or 3,5-dihydroazepine derivatives depending on the substituents… read more here.
Keywords: cyclization allenynes; driven bcl3; allenynes driven; borylative cyclization ... See more keywords
Copper-Catalyzed Borylative Cyclization of Substituted N-(2-Vinylaryl)benzaldimines.
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DOI: 10.1021/acs.orglett.8b00213
Abstract: A t-BuOCu-initiated reaction sequence of styrene borometalation and intramolecular imine addition has been achieved using a Cu(OTf)2/dppf combination as catalyst. The product of this reaction cascade is a useful 2,3-disubstituted indoline bearing a versatile boryl… read more here.
Keywords: substituted vinylaryl; copper catalyzed; cyclization substituted; borylative cyclization ... See more keywords
Radical Borylative Cyclization of 1,6-Dienes: Synthesis of Boron-Substituted Six-Membered Heterocycles and Carbocycles.
Sign Up to like & getrecommendations! Published in 2018 at "Organic letters"
DOI: 10.1021/acs.orglett.8b00694
Abstract: A radical borylative cyclization reaction of 1,6-dienes was developed to assemble boron-handled six-membered heterocycles and carbocycles. This reaction was initiated by the chemo- and regio-controlled addition of an N-heterocyclic carbene-boryl radical to one of the… read more here.
Keywords: six membered; cyclization; radical borylative; membered heterocycles ... See more keywords