Predictive model of bosentan-induced liver toxicity in Japanese patients with pulmonary arterial hypertension.
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DOI: 10.1139/cjpp-2019-0656
Abstract: Bosentan, an endothelin receptor antagonist, has been widely used as a first-line medication for the treatment of pulmonary arterial hypertension (PAH). However, liver dysfunction is a major side effect of bosentan treatment that could hamper… read more here.
Keywords: liver toxicity; bosentan induced; model; induced liver ... See more keywords